RNA折叠算法是如何工作的？
How do RNA folding algorithms work?
作者信息
Eddy Sean R
机构信息
Howard Hughes Medical Institute & Department of Genetics, Washington University School of Medicine, 4444 Forest Park Blvd., Box 8510, Saint Louis, Missouri 63108, USA.
出版信息
Nat Biotechnol. 2004 Nov;22(11):1457-8. doi: 10.1038/nbt1104-1457.
PMID:15529172
Abstract
Programs such as MFOLD and ViennaRNA are widely used to predict RNA secondary structures. How do these algorithms work? Why can't they predict RNA pseudoknots? How accurate are they, and will they get better?
摘要
诸如MFOLD和ViennaRNA之类的程序被广泛用于预测RNA二级结构。这些算法是如何工作的？它们为什么不能预测RNA假结？它们的准确性如何，以及会变得更好吗？
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