Steffen Peter, Voss Björn, Rehmsmeier Marc, Reeder Jens, Giegerich Robert
Faculty of Technology and, Bielefeld University, 33594 Bielefeld, Germany.
Bioinformatics. 2006 Feb 15;22(4):500-3. doi: 10.1093/bioinformatics/btk010. Epub 2005 Dec 15.
We introduce RNAshapes, a new software package that integrates three RNA analysis tools based on the abstract shapes approach: the analysis of shape representatives, the calculation of shape probabilities and the consensus shapes approach. This new package is completely reimplemented in C and outruns the original implementations significantly in runtime and memory requirements. Additionally, we added a number of useful features like suboptimal folding with correct dangling energies, structure graph output, shape matching and a sliding window approach.
我们介绍了RNAshapes,这是一个新的软件包,它基于抽象形状方法集成了三种RNA分析工具:形状代表分析、形状概率计算和共有形状方法。这个新软件包完全用C语言重新实现,在运行时和内存需求方面比原来的实现有显著提升。此外,我们还添加了许多有用的功能,如具有正确悬垂能量的次优折叠、结构图输出、形状匹配和滑动窗口方法。