Abe F
Extremobiosphere Research Center, Japan Agency for Marine-Earth Science and Technology (JAMSTEC), Yokosuka, Japan.
Cell Mol Biol (Noisy-le-grand). 2004 Jun;50(4):437-45.
Hydrostatic pressure is a thermodynamic parameter that has recently received further consideration in various experimental fields. Although the physicochemical basis of pressure effects is well established, the effects of high pressure on in vivo biological processes have not been systematically investigated due to its presumed complexity. The word "piezophysiology" was proposed to describe the unique cellular responses to high pressure in living cells. The yeast Saccharomyces cerevisiae is one of the best-characterized organisms in many fields in bioscience. Here I review the accumulated literature on cellular responses to increasing hydrostatic pressure in yeast, focusing on survival, growth, gene expression and metabolism.
流体静压是一种热力学参数，最近在各个实验领域受到了更多关注。尽管压力效应的物理化学基础已得到充分确立，但由于其假定的复杂性，高压对体内生物过程的影响尚未得到系统研究。“压力生理学”一词被提出来描述活细胞对高压的独特细胞反应。酿酒酵母是生物科学许多领域中特征最明显的生物体之一。在此，我回顾了关于酵母细胞对不断增加的流体静压反应的累积文献，重点关注生存、生长、基因表达和代谢。
