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[口服铁剂的生物利用度。藻酸盐/抗酸剂给药的影响]

[Bioavailability of orally administered iron. Effects of alginate/antacid administration].

作者信息

Campo S, Breda E

机构信息

Divisione di Medicina, Ospedale S. Giovanni Calibita, Fatebenefratelli, Isola Tiberina, Roma.

出版信息

Minerva Med. 1992 Mar;83(3):145-7.

PMID:1553063
Abstract

Sideropenia is often encountered in medical practice; the iron preparation that presents the highest bioavailability is unquestionably iron sulphate. This compound, however, frequently provokes numerous side-effects that induce the patient to suspend treatment. Here it is shown that the bioavailability of the drug is not changed after intake of alginic acid, while side-effects are considerably reduced.

摘要

缺铁性贫血在医疗实践中经常遇到;生物利用度最高的铁制剂无疑是硫酸亚铁。然而,这种化合物经常引发许多副作用,导致患者中断治疗。本文表明,摄入海藻酸后药物的生物利用度没有改变,而副作用却大大减少。

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