Suppr超能文献

通过13C-辛酸呼气试验评估补充矿泉水对功能性消化不良患者固体食物胃排空的影响。

Effects of mineral-water supplementation on gastric emptying of solids in patients with functional dyspepsia assessed with the 13C-octanoic-acid breath test.

作者信息

Anti Marcello, Lippi Maria Enrichetta, Santarelli Luca, Gabrielli Maurizio, Gasbarrini Antonio, Gasbarrini Giovanni

机构信息

Department of Internal Medicine, Catholic University of the Sacred Heart, Rome, Italy.

出版信息

Hepatogastroenterology. 2004 Nov-Dec;51(60):1856-9.

Abstract

BACKGROUND/AIMS: Functional dyspepsia is a major problem in terms of prevalence and drug-therapy expenditures. In dyspeptic patients the symptoms are frequently caused by delayed gastric emptying. Conventional treatment is often inefficient. Mineral-water supplementation is prescribed for the treatment of this condition, but there is no concrete proof of its actual efficacy. The aim of this study was to evaluate the effect of supplementation with mineral waters with high mineral salt contents (Acqua Tettuccio, Acqua Regina, Montecatini Terme) on gastric emptying of solids and symptoms in patients with functional dyspepsia.

METHODOLOGY

Eight patients with functional dyspepsia and two healthy (non-dyspeptic) controls were placed on high-mineral-content water supplementation (500 cc/day) for eight days. Before and after completion of the supplementation treatment, patient symptoms were scored and the 13C-octanoic-acid breath test was administered to assess gastric emptying.

RESULTS

After the treatment, the dyspeptic subjects presented clear decreases in parameters of gastric emptying (half time and lag time) as well as an improvement in symptom scores.

CONCLUSIONS

Health spa treatments based on consumption of waters with a high content of mineral salts seem to be capable of improving gastric emptying of solids in dyspeptics. Longer and longitudinal studies are needed to verify the persistence of this effect.

摘要

背景/目的:功能性消化不良在患病率和药物治疗费用方面都是一个主要问题。在消化不良患者中,症状通常由胃排空延迟引起。传统治疗往往效果不佳。虽有采用补充矿泉水治疗这种情况的医嘱,但尚无其实际疗效的确切证据。本研究的目的是评估补充高矿盐含量的矿泉水(泰图乔矿泉水、女王矿泉水、蒙特卡蒂尼泰尔梅矿泉水)对功能性消化不良患者固体食物胃排空及症状的影响。

方法

8例功能性消化不良患者和2例健康(无消化不良)对照者接受高矿盐含量水补充(500毫升/天),为期8天。在补充治疗前后,对患者症状进行评分,并进行13C - 辛酸呼气试验以评估胃排空情况。

结果

治疗后,消化不良受试者的胃排空参数(半衰期和延迟时间)明显降低,症状评分也有所改善。

结论

基于饮用高矿盐含量水的温泉疗法似乎能够改善消化不良患者的固体食物胃排空。需要进行更长时间的纵向研究来验证这种效果的持续性。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验