胆囊结石患者胆囊切除术前及术后的胃排空情况。

Gastric emptying before and after cholecystectomy in patients with cholecystolithiasis.

作者信息

Vignolo Maria Cristina, Savassi-Rocha Paulo Roberto, Coelho Luiz Gonzaga Vaz, Soares Marcela Penna, Cardoso-Júnior Aloísio, Barbosa Teresa Fabiola Leo, Ramos Fabiana Viana, Alves Tatiana Rodrigues, Barbosa Gerdson Magno, Pinto Daniele Cristine Gomes, Resende Clarissa de Carvalho, Boechat Lucas de Castro, de Almeida Aline Miranda

机构信息

Alfa Institute of Gastroenterology, University Hospital, Faculty of Medicine Federal University of Minas Gerais, Belo Horizonte, Brazil.

出版信息

Hepatogastroenterology. 2008 May-Jun;55(84):850-4.

PMID:18705281

Abstract

BACKGROUND/AIMS: The objective of the present study was to measure gastric emptying time of solids and semisolids in dyspeptic individuals with cholecystolithiasis before and 6 months after cholecystectomy in order to determine whether cholecystectomy interferes with gastric emptying.

METHODOLOGY

A prospective, self-pairing study was conducted on 29 patients selected according to appropriate inclusion and exclusion criteria. Gastric emptying time of solids and semisolids was determined before and six months after laparoscopic cholecystectomy by the 13C-octanoic acid and 13C-acetate breath tests, respectively. The samples were analyzed by infrared spectrometry. The gastric retention time (lag phase) and gastric emptying half-time of solid and semisolid were determined and the results obtained before and after surgery were compared in the same patient. In addition, the effects of surgery on dyspeptic symptoms were assessed.

RESULTS

No significant differences (p>0.05) in gastric retention time and gastric emptying half-time of solid and semisolid test meals were observed before and after cholecystectomy. Dyspeptic symptoms (pain, upper abdominal gases, early satiety, nausea and vomiting) improved after surgery.

CONCLUSIONS

Laparoscopic cholecystectomy does not interfere with the gastric emptying time of solids or semisolids in dyspeptic individuals with cholecystolithiasis.

摘要

背景/目的：本研究的目的是测量患有胆囊结石的消化不良患者在胆囊切除术前及术后6个月时固体和半固体食物的胃排空时间，以确定胆囊切除术是否会干扰胃排空。

方法

根据适当的纳入和排除标准，对29例患者进行了一项前瞻性自身配对研究。分别通过13C-辛酸呼气试验和13C-乙酸呼气试验测定腹腔镜胆囊切除术前及术后6个月时固体和半固体食物的胃排空时间。样本通过红外光谱法进行分析。测定固体和半固体食物的胃潴留时间（延迟期）和胃排空半衰期，并在同一患者中比较手术前后的结果。此外，评估手术对消化不良症状的影响。