Sfarti C, Trifan Anca, Huţănaşu C, Cojocariu Camelia, Sîngeap Ana-Maria, Stanciu C
Institutul de Gastroenterologie si Hepatologie Iaşi, Facultatea de Medicină, Universitatea de Medicină si Farmacie "Gr.T. Popa" Iaşi.
Rev Med Chir Soc Med Nat Iasi. 2009 Oct-Dec;113(4):1040-7.
The relationship between functional dyspepsia and delayed gastric emptying of solids is still unclear. This study evaluated the prevalence of delayed gastric emptying of solids in functional dyspepsia patients and its relationship to dyspeptic symptoms.
142 patients with functional dyspepsia were prospectively assessed, the solid gastric emptying was measured using 13C-acid octanoic breath test and the severity of six dyspeptic symptoms (postprandial fullness, early satiety, bloating, abdominal discomfort, nausea and vomiting) was scored.
Gastric emptying of solids was delayed in 45 (31.7%) dyspeptic patients. Multivariate analysis showed that the presence and severity of nausea and vomiting were associated with delayed solid gastric emptying (p < 0.05). Female gender was also associated with the risk of delayed gastric emptying (p < 0.05).
A subset of functional dyspepsia patients has delayed gastric emptying of solids. Female sex, the presence and severity of nausea and vomiting are independently associated with delayed gastric emptying of solids in these patients.
功能性消化不良与固体食物胃排空延迟之间的关系仍不清楚。本研究评估了功能性消化不良患者固体食物胃排空延迟的患病率及其与消化不良症状的关系。
对142例功能性消化不良患者进行前瞻性评估，采用13C-辛酸呼气试验测量固体食物胃排空情况，并对六种消化不良症状（餐后饱胀、早饱、腹胀、腹部不适、恶心和呕吐）的严重程度进行评分。
45例（31.7%）消化不良患者存在固体食物胃排空延迟。多因素分析显示，恶心和呕吐的存在及严重程度与固体食物胃排空延迟相关（p<0.05）。女性也与胃排空延迟风险相关（p<0.05）。
一部分功能性消化不良患者存在固体食物胃排空延迟。在这些患者中，女性、恶心和呕吐的存在及严重程度与固体食物胃排空延迟独立相关。
