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经椎弓根入路治疗胸椎结核:一项短期随访研究

The transpedicular approach in the management of thoracic spine tuberculosis: a short-term follow up study.

作者信息

Chacko Ari G, Moorthy Ranjith K, Chandy Mathew J

机构信息

Section of Neurosurgery, Department of Neurological Sciences, Christian Medical College and Hospital, Vellore 632004, India.

出版信息

Spine (Phila Pa 1976). 2004 Sep 1;29(17):E363-7. doi: 10.1097/01.brs.0000137063.64650.e1.

Abstract

STUDY DESIGN

A retrospective descriptive assessment of the clinical and radiologic outcomes of 11 patients who underwent transpedicular decompression for thoracic spine tuberculosis.

OBJECTIVES

To study the neurologic and radiologic outcomes in patients who underwent transpedicular decompression for thoracic spine tuberculosis.

SUMMARY OF BACKGROUND DATA

Several approaches have been used in the management of thoracic spine tuberculosis to achieve the goals of decompression of the cord followed by immobilization and antituberculous therapy. These range from conservative regimens of computed tomography-guided biopsy followed by bed rest and drug therapy to radical surgeries that involve extensive debridement of the vertebral body followed by instrumentation. The authors report their experience with a "middle path" regimen of transpedicular decompression followed by external immobilization and antituberculous therapy.

METHODS

The charts of 11 patients were reviewed retrospectively for clinical outcome, and kyphotic angle was measured on the follow-up radiographs to ascertain progression of kyphosis.

RESULTS

There was no worsening of the neurologic status in any patient, and 10 of the 11 patients returned to functional activity. There was no significant progression of kyphosis.

CONCLUSIONS

Our results show that the transpedicular approach is a viable and safe surgical option for ventral decompression in thoracic spine tuberculosis, followed by chemotherapy for 18 months and immobilization in an alkathene shell for 3 months.

摘要

研究设计

对11例行胸椎结核经椎弓根减压术患者的临床和影像学结果进行回顾性描述性评估。

目的

研究行胸椎结核经椎弓根减压术患者的神经功能和影像学结果。

背景资料总结

在胸椎结核的治疗中,已采用多种方法来实现脊髓减压、固定和抗结核治疗的目标。这些方法从计算机断层扫描引导下活检后的保守方案(随后卧床休息和药物治疗)到涉及椎体广泛清创并随后进行内固定的根治性手术。作者报告了他们采用经椎弓根减压、外固定和抗结核治疗的“中间路径”方案的经验。

方法

回顾性分析11例患者的病历以评估临床结果,并在随访X线片上测量后凸角以确定后凸畸形的进展情况。

结果

所有患者神经功能均未恶化,11例患者中有10例恢复了功能活动。后凸畸形无明显进展。

结论

我们的结果表明,经椎弓根入路是胸椎结核前路减压的一种可行且安全的手术选择,随后进行18个月的化疗,并在聚乙烯壳内固定3个月。

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