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[硬膜外脊髓刺激治疗慢性顽固性心绞痛]

[Epidural spinal cord stimulation in chronic refractory angina pectoris].

作者信息

Myran Rigmor, Jørgensen Jan V, Wiseth Rune

机构信息

Nevrokirurgisk avdeling, St. Olavs Hospital, 7006 Trondheim.

出版信息

Tidsskr Nor Laegeforen. 2004 Nov 4;124(21):2754-6.

Abstract

BACKGROUND

Chronic refractory angina pectoris is defined as a condition with coronary insufficiency that cannot be controlled by a combination of medical therapy, angioplasty or bypass surgery. Different treatment options are evaluated in this patient group; spinal cord stimulation (SCS) is the one that is best documented. We have used this method since 1996 and present our experience.

MATERIALS AND METHODS

From 1996 to 2001, spinal cord stimulators were implanted in 21 patients. A follow-up study was performed after 27 months (range 7-71) with a questionnaire. Preoperative clinical and angiographic data were retrieved from our records.

RESULTS

17 men and 4 women aged 55-88 years (median 73) were treated with SCS. Preoperatively all patients were in CCS (Canadian Cardiovascular Society) class III-IV. 81% had previously undergone coronary artery bypass surgery. At follow up, 81% were alive. Lead fracture occurred in two patients, displacement of the electrode in one. There were no other complications. 71% reported symptomatic improvement, mean CCS class was reduced from 3.5 prior to SCS to 2.2 at follow up, and use of nitroglycerin was reduced.

INTERPRETATION

In chronic refractory angina pectoris, spinal cord stimulation is an alternative. We report "beginners' experience" that is positive including substantial symptomatic effect and a low complication rate. More hospitals in Norway should consider establishing SCS in order to offer this treatment option to a growing patient group.

摘要

背景

慢性难治性心绞痛被定义为一种冠状动脉供血不足的病症,无法通过药物治疗、血管成形术或搭桥手术的联合治疗得到控制。在这一患者群体中评估了不同的治疗选择;脊髓刺激(SCS)是记录最完善的一种。自1996年以来我们一直使用这种方法,并介绍我们的经验。

材料与方法

1996年至2001年,对21例患者植入了脊髓刺激器。27个月(范围7 - 71个月)后通过问卷调查进行了随访研究。从我们的记录中获取术前临床和血管造影数据。

结果

17名男性和4名女性,年龄55 - 88岁(中位数73岁)接受了SCS治疗。术前所有患者均为加拿大心血管学会(CCS)III - IV级。81%的患者此前接受过冠状动脉搭桥手术。随访时,81%的患者存活。两名患者发生导联断裂,一名患者电极移位。无其他并发症。71%的患者报告症状改善,平均CCS分级从SCS术前的3.5级降至随访时的2.2级,硝酸甘油的使用减少。

解读

在慢性难治性心绞痛中,脊髓刺激是一种替代方法。我们报告了积极的“初学者经验”,包括显著的症状改善效果和低并发症发生率。挪威更多的医院应考虑开展SCS,以便为不断增加的患者群体提供这种治疗选择。

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