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国立心脏研究所主动脉缩窄修复术(1983 - 1994年)

Coarctation of aorta repair at the National Heart Institute (1983-1994).

作者信息

Adeeb S M S J, Leman H, Sallehuddin A, Yakub A, Awang Y, Alwi M

机构信息

Division of Cardiothoracic Surgery, Department of Surgery, Hospital University Kebangsaan Malaysia, Kuala Lumpur.

出版信息

Med J Malaysia. 2004 Mar;59(1):11-4.

Abstract

This retrospective study illustrates our approach to this problem over the years, from performing subclavian flap aortoplasty initially to the more accepted procedure now, which is resection and end-to-end anastomosis. Coarctation of aorta in our population is seen in a varying age groups and are also associated with other cardiac anomalies including both acyanotic and cyanotic congenital cardiac defects. Therefore a wide variety of surgical procedures were performed including resection of the coarcted segment and end-to-end anastomosis, subclavian flap aortoplasty, patch aortoplasty and synthetic tube graft interposition. Subclavian flap aortoplasty is not widely practised anymore in favour of resection with end-to-end anastomosis. Fifty four point four percent of patients had isolated coarctation, 10.5% had associated valvular defects, 28.1% had other simple congenital defects and 7.0% had associated complex cyanotic congenital defects. Perioperative mortality was 5.26% and is correlated with the younger age of patients at time of surgery and severity of cardiac failure at time of presentation. We did not see any difference in mortality for patients with complex congenital disease or between the different surgical procedures. However, we did find that in the early period when resection with end-to-end anastomosis was performed, there was a significantly higher incidence of morbidities.

摘要

这项回顾性研究阐述了我们多年来针对该问题所采用的方法,从最初施行锁骨下动脉瓣主动脉成形术到如今更被广泛接受的手术方式,即切除并端端吻合术。在我们的研究人群中,主动脉缩窄可见于不同年龄组,且还与其他心脏异常相关,包括无青紫型和青紫型先天性心脏缺陷。因此,我们实施了多种外科手术,包括切除缩窄段并进行端端吻合术、锁骨下动脉瓣主动脉成形术、补片主动脉成形术以及人工血管置换术。如今,锁骨下动脉瓣主动脉成形术已不再广泛应用,而更倾向于采用切除并端端吻合术。54.4%的患者为单纯性主动脉缩窄,10.5%的患者伴有瓣膜缺陷,28.1%的患者伴有其他简单先天性缺陷,7.0%的患者伴有复杂青紫型先天性缺陷。围手术期死亡率为5.26%,且与手术时患者年龄较小以及就诊时心力衰竭的严重程度相关。我们未发现复杂先天性疾病患者之间或不同手术方式之间在死亡率上存在差异。然而,我们确实发现,在早期施行切除并端端吻合术时,并发症的发生率显著更高。

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