Ralph-Edwards A C, Williams W G, Coles J C, Rebeyka I M, Trusler G A, Freedom R M
Division of Cardiac Surgery, University of Toronto, Hospital for Sick Children, Ontario, Canada.
Ann Thorac Surg. 1995 Nov;60(5):1303-7. doi: 10.1016/0003-4975(95)00619-V.
Recurrence of stenosis is a complication of coarctation repair associated with major long-term morbidity. Persistent or exercise-provoked hypertension may indicate recurrent coarctation. Patients failing or not amenable to balloon dilation should be managed surgically.
A retrospective chart review was performed.
Forty-three patients were identified as having undergone repeat surgical intervention for recurrent aortic coarctation between the years 1976 and 1993 at The Hospital for Sick Children in Toronto. Seventy percent of the children had other congenital cardiac anomalies. Eighty-six percent of patients initially treated by subclavian flap aortoplasty or end-to-end anastomosis were managed at reoperation by patch aortoplasty, and 26% of patients also required augmentation of the transverse arch (under hypothermic circulatory arrest) for accompanying hypoplasia. Three patients underwent a second reoperation; all were treated at this reoperation with tube graft interposition.
No ischemic spinal injury occurred in patients managed with either simple proximal aortic cross-clamping or cardiopulmonary bypass. No patient treated with transverse arch augmentation required further surgical intervention. Mortality at reoperation was 7% (3 patients), similar to that of first-time coarctation repair. At follow-up (mean duration, 4.5 years), 57% of patients are normotensive, with no measurable arm-leg gradient.
狭窄复发是主动脉缩窄修复术的一种并发症,与严重的长期发病率相关。持续性或运动诱发的高血压可能提示主动脉缩窄复发。对于球囊扩张失败或不适合球囊扩张的患者,应进行手术治疗。
进行了一项回顾性病历审查。
确定43例患者于1976年至1993年期间在多伦多病童医院因复发性主动脉缩窄接受了再次手术干预。70%的儿童患有其他先天性心脏异常。最初接受锁骨下皮瓣主动脉成形术或端端吻合术治疗的患者中,86%在再次手术时采用补片主动脉成形术,26%的患者还因伴有主动脉弓发育不全而需要在低温循环停止下扩大主动脉弓。3例患者接受了第二次再次手术;所有患者在此次再次手术时均采用人工血管置换术治疗。
单纯近端主动脉交叉钳夹或体外循环治疗的患者未发生缺血性脊髓损伤。接受主动脉弓扩大术治疗的患者均无需进一步手术干预。再次手术的死亡率为7%(3例患者),与首次主动脉缩窄修复术相似。在随访(平均时长4.5年)时,57%的患者血压正常,上肢与下肢无明显压差。