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锁骨下动脉瓣主动脉成形术:仍是治疗婴儿主动脉缩窄的一种安全、可重复且有效的方法。

Subclavian flap aortoplasty: still a safe, reproducible, and effective treatment for infant coarctation.

作者信息

Barreiro Christopher J, Ellison Trevor A, Williams Jason A, Durr Megan L, Cameron Duke E, Vricella Luca A

机构信息

Division of Cardiac Surgery, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.

出版信息

Eur J Cardiothorac Surg. 2007 Apr;31(4):649-53. doi: 10.1016/j.ejcts.2006.12.038. Epub 2007 Feb 5.

Abstract

OBJECTIVE

Subclavian flap repair of infant coarctation has been criticized and in many centers abandoned in favor of resection with end-to-end anastomosis. The goal of this study was to examine intermediate and long-term results of infant subclavian flap aortoplasty, which has been the preferred technique at our institution over the last two decades.

METHODS

Our patient database identified all infants (age<1 year) who underwent repair of isthmic coarctation via thoracotomy between January 1984 and December 2004. Procedure details and late results were collected by retrospective review of hospital and clinic data. Follow-up was 95.8% complete at a mean of 6.7 years.

RESULTS

Between January 1984 and December 2004, 119 infants underwent isolated subclavian flap repair of coarctation. Mean age and weight at operation were 35+/-52 days (range 1-269 days) and 3.5+/-1.3kg (range 0.7-9.3kg), respectively. Concomitant pulmonary artery banding was performed in 22% (26/119). In-hospital mortality was 4% (5/119) and cumulative late mortality was 6% (7/114) of patients with long-term follow-up. Actuarial survival at 1, 5, and 10 years was 91, 85, and 85%, respectively. Overall re-intervention rate for re-stenosis was 11% (12/114); 10 patients (9%) underwent balloon angioplasty while 3 patients (3%) required operative revision. All re-stenoses occurred in the descending aorta, and all occurred in patients who had undergone neonatal repair. At late follow-up, there were no significant neurologic events (left recurrent laryngeal nerve injury, stellate ganglion dysfunction, or paraplegia), no clinically significant ischemic arm complications, and no flap aneurysms.

CONCLUSIONS

Subclavian flap aortoplasty remains our procedure of choice for isthmic coarctation, as it is a simple, technically straightforward technique with a low incidence of re-stenosis and serious early and late morbidity. Furthermore, subclavian flap re-stenoses are easily treated with percutaneous intervention and seldom require surgical re-intervention via thoracotomy.

摘要

目的

婴儿锁骨下动脉瓣修补法治疗主动脉缩窄受到批评,在许多中心已被摒弃,转而采用端端吻合切除术。本研究的目的是探讨婴儿锁骨下动脉瓣主动脉成形术的中期和长期效果,在过去二十年中,该技术一直是我们机构的首选方法。

方法

我们的患者数据库确定了1984年1月至2004年12月期间所有经开胸手术修复峡部型主动脉缩窄的婴儿(年龄<1岁)。通过回顾医院和诊所数据收集手术细节和后期结果。随访率为95.8%,平均随访时间为6.7年。

结果

1984年1月至2004年12月期间,119例婴儿接受了单纯锁骨下动脉瓣修补主动脉缩窄手术。手术时的平均年龄和体重分别为35±52天(范围1 - 269天)和3.5±1.3kg(范围0.7 - 9.3kg)。22%(26/119)的患者同时进行了肺动脉环扎术。住院死亡率为4%(5/119),长期随访患者的累积晚期死亡率为6%(7/114)。1年、5年和10年的精算生存率分别为91%、85%和85%。再狭窄的总体再次干预率为11%(12/114);10例患者(9%)接受了球囊血管成形术,3例患者(3%)需要手术翻修。所有再狭窄均发生在降主动脉,且均发生在接受新生儿期修复的患者中。在后期随访中,未发生明显的神经系统事件(左侧喉返神经损伤、星状神经节功能障碍或截瘫),无具有临床意义的缺血性手臂并发症,也无瓣动脉瘤形成。

结论

锁骨下动脉瓣主动脉成形术仍然是我们治疗峡部型主动脉缩窄的首选方法,因为它是一种简单、技术上直接的技术,再狭窄发生率低,早期和晚期严重并发症发生率也低。此外,锁骨下动脉瓣再狭窄很容易通过经皮介入治疗,很少需要通过开胸手术进行再次干预。

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