Khoo J J
Department of Pathology, Hospital Sultanah Aminah, 80100 Johor Bahru.
Med J Malaysia. 2004 Mar;59(1):50-5.
A 4-year-review was carried out on intraoperative frozen section consultations in Sultanah Aminah Hospital, Johor Bahru. Two hundred and fifteen specimens were received from 79 patients in the period between January 1999 and December 2002. An average of 2.72 specimens per patient was received. The overall diagnostic accuracy was high, 97.56%. The diagnoses were deferred in 4.65% of the specimens. False positive diagnoses were made in 3 specimens (1.46%) and false negative diagnoses in 2 specimens (0.98%). This gave an error rate of 2.44%. The main cause of error was incorrect interpretation of the pathologic findings. In the present study, frozen sections showed good sensitivity (97.98%) and specificity (97.16%). Despite its limitations, frozen section is still generally considered to be an accurate mode of intraoperative consultation to assist the surgeon in deciding the best therapeutic approach for his patient at the operating table. The use of frozen section with proper indications was cost-effective as it helped lower the number of reoperations. An audit of intraoperative frozen section from time to time serves as part of an ongoing quality assurance program and should be recommended where the service is available.
对柔佛州新山市苏丹娜阿米娜医院的术中冰冻切片会诊进行了为期4年的回顾性研究。在1999年1月至2002年12月期间,从79名患者处接收了215份标本。平均每名患者接收2.72份标本。总体诊断准确率较高,为97.56%。4.65%的标本诊断结果被延迟。3份标本(1.46%)出现假阳性诊断,2份标本(0.98%)出现假阴性诊断。这使得错误率为2.44%。错误的主要原因是对病理结果的解读不正确。在本研究中,冰冻切片显示出良好的敏感性(97.98%)和特异性(97.16%)。尽管存在局限性,但冰冻切片仍通常被认为是一种准确的术中会诊方式,可帮助外科医生在手术台上为患者决定最佳治疗方法。在有适当指征的情况下使用冰冻切片具有成本效益,因为它有助于减少再次手术的次数。定期对术中冰冻切片进行审核是持续质量保证计划的一部分,在有该项服务的地方应予以推荐。