Lickey Marvin E, Pham Tony A, Gordon Barbara
Institute of Neuroscience, 1254 University of Oregon, Eugene, OR 97403, USA.
Vision Res. 2004 Dec;44(28):3381-7. doi: 10.1016/j.visres.2004.09.018.
The swept contrast visual evoked potential technique is a quasi-psychophysical method that can help bridge the gap between cell biology and visual performance in studies of ocular dominance plasticity. In mice we found that four days of monocular deprivation diminished the amplitude of evoked potentials from the deprived eye relative to the non-deprived eye. This ocular dominance plasticity was nearly as great in adult mice as in juveniles. The monocular deprivation effect was mediated, at least in part, by enhancement of responses evoked from the non-deprived eye, rather than by depression of responses from the deprived eye.
扫频对比视觉诱发电位技术是一种准心理物理学方法，在眼优势可塑性研究中有助于弥合细胞生物学与视觉表现之间的差距。在小鼠中我们发现，四天的单眼剥夺会使被剥夺眼诱发的电位幅度相对于未被剥夺眼减小。这种眼优势可塑性在成年小鼠中几乎与幼年小鼠一样大。单眼剥夺效应至少部分是由未被剥夺眼诱发反应的增强介导的，而不是由被剥夺眼反应的抑制介导的。
