Gullestad L, Kjekshus J
Medisinsk avdeling B, Rikshospitalet, Oslo.
Tidsskr Nor Laegeforen. 1992 Mar 20;112(8):1016-9.
Diabetes mellitus is associated with excessive cardiovascular morbidity and mortality. Patients with diabetes mellitus suffer premature and severe atherosclerosis, and the relative impact is greater in women than in men. Clinical, experimental and pathological studies support the existence of a specific cardiomyopathy associated with diabetes mellitus. The cardiomyopathy plays an essential role in the pathogenesis of primary myocardial involvement, resulting in ventricular dysfunction, diminished cardiac pump performance and eventually overt heart failure. The authors discuss coronary heart disease and diabetic cardiomyopathy and indicate relevant treatment regimens.
糖尿病与心血管疾病的高发病率和高死亡率相关。糖尿病患者会出现过早且严重的动脉粥样硬化，且这种影响在女性中比在男性中更为显著。临床、实验和病理学研究均支持存在一种与糖尿病相关的特定心肌病。这种心肌病在原发性心肌受累的发病机制中起关键作用，导致心室功能障碍、心脏泵血功能减弱，最终发展为明显的心衰。作者讨论了冠心病和糖尿病性心肌病，并指出了相关的治疗方案。
