Cavendish Jeffrey J, Cramer Steven C, Graham Glenn D
Department of Cardiology, Naval Medical Center, San Diego, CA 92134, USA.
Curr Med Res Opin. 2004 Nov;20(11):1845-9. doi: 10.1185/030079904X10674.
The etiology of cerebrovascular disease is heterogeneous, with the majority of strokes being of ischemic origin. Transient ischemic attack is now considered to be an important precursor and long-term risk factor for ischemic stroke. Given the lack of acute therapies for ischemic stroke, current treatments focus on secondary prevention through risk-factor management, pharmacotherapy and interventional approaches. As illustrated in this paper, antiplatelet agents (e.g. clopidogrel, aspirin, dipyridamole) are the cornerstone of therapy for prevention of recurrent ischemic stroke.
脑血管疾病的病因多种多样，大多数中风是缺血性的。短暂性脑缺血发作现在被认为是缺血性中风的重要先兆和长期危险因素。鉴于缺血性中风缺乏急性治疗方法，目前的治疗重点是通过危险因素管理、药物治疗和介入方法进行二级预防。如本文所示，抗血小板药物（如氯吡格雷、阿司匹林、双嘧达莫）是预防复发性缺血性中风治疗的基石。
