Kim Jeong Ho, Kim Hyung-Jin, Lee Kyung-Hee, Kim Kwang Ho, Lee Hong Lyeol
Department of Radiology, Inha University Hospital, Incheon, Republic of Korea.
J Comput Assist Tomogr. 2004 Nov-Dec;28(6):766-75. doi: 10.1097/00004728-200411000-00007.
The aim of this prospective study was to compare the diagnostic performances of dynamic MR imaging and CT for the differentiation of benign and malignant solitary pulmonary nodules (SPNs).
Eighty-one patients with SPNs (32 malignant, 49 benign) underwent dynamic MR imaging (n=31), dynamic CT (n=27), or both (n=23). The degree of peak enhancement of benign and malignant SPNs was compared on both dynamic MR imaging and CT. Receiver operating characteristic (ROC) analysis was performed to compare the diagnostic performances of dynamic MR imaging and CT.
The malignant SPNs revealed significantly greater degrees of peak enhancement on dynamic MR imaging (mean +/- SD [p%SI] 131.2 +/- 46.1 versus 54.2 +/- 45.3; range [p%SI] 82.6-260.0 versus -0.7-171.7; P <0.0001) and CT (mean +/- SD [DMI] 37.8 +/- 15.1 versus 17.9 +/- 21.8; range [DMI] 14.1-68.2 versus -5.4-107.6; P=0.0004). Although dynamic MR imaging was somewhat superior to dynamic CT, the diagnostic performances of the 2 modalities based on ROC analysis were not statistically significant.
Dynamic MR imaging and CT seem to be equally well suited for the differentiation between benign and malignant SPNs.
本前瞻性研究旨在比较动态磁共振成像（MRI）和计算机断层扫描（CT）对鉴别良性和恶性孤立性肺结节（SPN）的诊断性能。
81例SPN患者（32例恶性，49例良性）接受了动态MRI（n = 31）、动态CT（n = 27）或两者（n = 23）检查。在动态MRI和CT上比较良性和恶性SPN的峰值强化程度。进行受试者操作特征（ROC）分析以比较动态MRI和CT的诊断性能。
恶性SPN在动态MRI上显示出明显更高的峰值强化程度（平均±标准差[p%SI] 131.2±46.1对54.2±45.3；范围[p%SI] 82.6 - 260.0对 - 0.7 - 171.7；P <0.0001）和CT（平均±标准差[DMI] 37.8±15.1对17.9±21.8；范围[DMI] 14.1 - 68.2对 - 5.4 - 107.6；P = 0.0004）。虽然动态MRI在某种程度上优于动态CT，但基于ROC分析的两种检查方式的诊断性能无统计学差异。
动态MRI和CT似乎同样适用于鉴别良性和恶性SPN。
