Mourad M, Desrousseaux B, Atat I, Abizeid G, Willocx P, Creusy C, Ampe J
Service de Chirurgie digestive et thoracique, Centre Hospitalier Saint Philibert, Lomme, France.
Acta Chir Belg. 1992 Jan-Feb;92(1):46-51.
Schwannomas as neurofibromas are neurogenic mesenchymal tumors of the stomach. They arise from the Schwann cells of nerves of th gastric wall and are usually benign. The incidence of malignant schwannomas is uncertain because of the variable pathologic criteria used. Immunohistochemistry is a diagnostic tool used to distinguish between schwannomas and leiomyomas both constituted by spindle-cells. In this issue we report a case of malignant schwannoma with lymph node involvement. The clinical and histological features of gastric schwannomas are discussed with evaluation of their diagnostic and therapeutic modalities.
神经鞘瘤与神经纤维瘤一样,都是胃的神经源性间叶组织肿瘤。它们起源于胃壁神经的施万细胞,通常为良性。由于所采用的病理标准不同,恶性神经鞘瘤的发病率尚不确定。免疫组织化学是一种用于区分均由梭形细胞构成的神经鞘瘤和平滑肌瘤的诊断工具。在本期中,我们报告了一例伴有淋巴结受累的恶性神经鞘瘤病例。本文讨论了胃神经鞘瘤的临床和组织学特征,并对其诊断和治疗方式进行了评估。