高剂量西咪替丁治疗转移性肾细胞癌。一项印第安纳肿瘤学组的研究。
High-dose cimetidine for the treatment of metastatic renal cell carcinoma. A Hoosier Oncology Group study.
作者信息
Inhorn L, Williams S D, Nattam S, Stephens D
机构信息
Oncology & Hematology Associates, Roanoke, Virginia.
出版信息
Am J Clin Oncol. 1992 Apr;15(2):157-9. doi: 10.1097/00000421-199204000-00012.
Abstract
The Hoosier Oncology Group evaluated cimetidine in 42 patients with metastatic renal cell carcinoma. There were two complete remissions that lasted for 26 and 33+ months in 38 evaluable patients. There were no partial remissions. Toxicity was minimal. Patients with renal cell carcinoma can occasionally respond to cimetidine with long-term remission.
摘要
印第安纳肿瘤学组对42例转移性肾细胞癌患者使用西咪替丁进行了评估。在38例可评估的患者中，有2例完全缓解，缓解期分别为26个月和33多个月。没有部分缓解的情况。毒性极小。肾细胞癌患者偶尔会对西咪替丁产生反应并获得长期缓解。
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