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一名接受血液透析、缺铁且正在服用奥美拉唑和口服铁补充剂的患者发生小肠结肠炎耶尔森菌败血症。

Septicemia due to Yersinia enterocolitica in a hemodialyzed, iron-depleted patient receiving omeprazole and oral iron supplementation.

作者信息

Fakir M, Saison C, Wong T, Matta B, Hardin J M

机构信息

Service d'Hémodialyse, Epuration extra-rénale-Médecine interne, Centre Hospitalier de Soissons, Reims, France.

出版信息

Am J Kidney Dis. 1992 Mar;19(3):282-4. doi: 10.1016/s0272-6386(13)80010-8.

Abstract

Septicemia occurred in a long-term hemodialysis patient on oral iron supplementation who had been treated for esophageal ulcer by omeprazole, an ulcer-healing drug. Yersinia enterocolitica serotype 0:3 was recovered from blood cultures. A raised intraintestinal pH and an increased intraluminal iron load may have been contributing factors for the enhanced proliferation and generalized infection of Y enterocolitica.

摘要

一名长期接受血液透析且正在口服补铁的患者发生了败血症,该患者曾使用溃疡愈合药物奥美拉唑治疗食管溃疡。从血培养中分离出小肠结肠炎耶尔森菌0:3血清型。肠内pH值升高和管腔内铁负荷增加可能是小肠结肠炎耶尔森菌增殖增强和全身感染的促成因素。

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