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怪异妄想与《精神疾病诊断与统计手册》第三版修订本中的精神分裂症

Bizarre delusions and DSM-III-R schizophrenia.

作者信息

Goldman D, Hien D A, Haas G L, Sweeney J A, Frances A J

机构信息

Department of Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213.

出版信息

Am J Psychiatry. 1992 Apr;149(4):494-9. doi: 10.1176/ajp.149.4.494.

DOI:10.1176/ajp.149.4.494
PMID:1554035
Abstract

OBJECTIVE

Bizarre delusions are assigned greater weight relative to other delusions in the DSM-III-R diagnosis of schizophrenia. The decision to emphasize bizarre delusions was based largely on historical tradition rather than empirical evidence. This study examined 1) the extent to which a history of bizarre delusions contributes to the diagnosis of schizophrenia and 2) whether schizophrenic patients with bizarre delusions constitute a clinically distinguishable subgroup.

METHOD

Two hundred fourteen consecutively admitted psychotic inpatients were assessed for bizarre delusions according to the DSM-III-R criteria. Clinical and demographic correlates of bizarre delusions were examined in subsets of patients diagnosed as schizophrenic according to DSM-III-R who also received CT scans and neuropsychological testing.

RESULTS

With the base prevalence rate for schizophrenia of 0.71, bizarre delusions had a sensitivity of 0.79, a specificity of 0.56, and a positive predictive power of 0.82 for the diagnosis of schizophrenia (N = 152) relative to other psychotic disorders (N = 62). Clinical, neurobehavioral, CT scan, and premorbid adjustment data on the schizophrenic patients indicated that beyond manifesting more severe positive symptoms, patients with bizarre delusions did not otherwise constitute a clinically distinguishable subgroup.

CONCLUSIONS

The data suggest that criterion A for the diagnosis of schizophrenia in DSM-IV could be improved by removing the special emphasis that was placed on bizarre delusions in DSM-III-R.

摘要

目的

在精神分裂症的《精神疾病诊断与统计手册》第三版修订本(DSM - III - R)诊断中,怪异妄想相对于其他妄想被赋予了更大权重。强调怪异妄想这一决定很大程度上基于历史传统而非实证依据。本研究考察了:1)怪异妄想病史对精神分裂症诊断的贡献程度;2)患有怪异妄想的精神分裂症患者是否构成一个临床上可区分的亚组。

方法

根据DSM - III - R标准,对214名连续入院的精神病住院患者进行怪异妄想评估。在根据DSM - III - R被诊断为精神分裂症且还接受了CT扫描和神经心理学测试的患者亚组中,检查怪异妄想的临床和人口统计学相关因素。

结果

相对于其他精神障碍(N = 62),精神分裂症的基础患病率为0.71时,怪异妄想对精神分裂症(N = 152)诊断的敏感性为0.79,特异性为0.56,阳性预测值为0.82。关于精神分裂症患者的临床、神经行为、CT扫描和病前适应数据表明,除了表现出更严重的阳性症状外,患有怪异妄想的患者在其他方面并不构成一个临床上可区分的亚组。

结论

数据表明,《精神疾病诊断与统计手册》第四版(DSM - IV)中精神分裂症诊断标准A可以通过去除DSM - III - R中对怪异妄想的特别强调而得到改进。

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