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精神分裂症患者与正常对照受试者的额叶、颞叶和纹状体质子弛豫时间

Frontal, temporal, and striatal proton relaxation times in schizophrenic patients and normal comparison subjects.

作者信息

Williamson P, Pelz D, Merskey H, Morrison S, Karlik S, Drost D, Carr T, Conlon P

机构信息

Department of Psychiatry, University of Western Ontario, London, Canada.

出版信息

Am J Psychiatry. 1992 Apr;149(4):549-51. doi: 10.1176/ajp.149.4.549.

Abstract

Spin-lattice (T1) and spin-spin (T2) magnetic resonance relaxation times were examined in frontal, temporal, and striatal regions of 24 patients with schizophrenia and 10 normal comparison subjects. The schizophrenic patients had more prolonged T2 values than did the comparison subjects, particularly in the left temporal cortex and white matter, suggesting tissue pathology.

摘要

对24名精神分裂症患者和10名正常对照者的额叶、颞叶和纹状体区域进行了自旋晶格(T1)和自旋-自旋(T2)磁共振弛豫时间检测。精神分裂症患者的T2值比对照者更长,尤其是在左侧颞叶皮质和白质,提示存在组织病理学改变。

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