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猪垂体中S-100蛋白的免疫组织化学定位

Immunohistochemical localization of S-100 protein in the pig pituitary gland.

作者信息

Marettová E, Maretta M

机构信息

Department of Anatomy, Histology and Physiology, University of Veterinary Medicine, Komenského 73, 041 81 Kosice, Slovakia.

出版信息

Anat Histol Embryol. 2004 Dec;33(6):344-7. doi: 10.1111/j.1439-0264.2004.00571.x.

DOI:10.1111/j.1439-0264.2004.00571.x
PMID:15540993
Abstract

Immunohistochemical localization of S-100 protein was studied in anterior, intermediate and posterior lobe of the pig pituitary gland. Two immunopositive cells for S-100 protein were identified: the folliculo-stellate cells (FSc) in the glandular lobes and the pituicytes in the neural lobe. In the anterior lobe, immunoreactive folliculo-stellate cells were scattered among secretory cells. In the area where the secretory cells form strands and follicle-like groups the positive cells were concentrated in groups. In the intermediate lobe, S-100 protein-positive cells were located sparsely among secretory cells and next to secretory follicles and the pituitary cleft. These FSc were more voluminous and displayed fewer cytoplasmic processes. In the neurohypophysis, positive reaction for S-100 protein was seen in the pituicytes. These cells were distributed singly or concentrated in groups. The distribution, and morphologic characteristics of the FSc in the glandular lobes and the pituicytes in the neural lobe in the pig indicate different origin of both S-100 protein-positive cells.

摘要

对猪垂体前叶、中叶和后叶中S-100蛋白进行免疫组织化学定位研究。鉴定出两种S-100蛋白免疫阳性细胞:腺叶中的滤泡星状细胞(FSc)和神经叶中的垂体细胞。在前叶,免疫反应性滤泡星状细胞散在于分泌细胞之间。在分泌细胞形成条索状和滤泡样团块的区域,阳性细胞聚集在一起。在中叶,S-100蛋白阳性细胞稀疏地位于分泌细胞之间、分泌滤泡和垂体裂附近。这些滤泡星状细胞体积更大,细胞质突起较少。在神经垂体中,垂体细胞可见S-100蛋白阳性反应。这些细胞单个分布或成群聚集。猪腺叶中滤泡星状细胞和神经叶中垂体细胞的分布及形态特征表明,这两种S-100蛋白阳性细胞起源不同。

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