Turhan Hasan, Erbay Ali Riza, Yasar Ayse Saatci, Balci Mustafa, Bicer Asuman, Yetkin Ertan
Department of Cardiology, Inonu University Medical Faculty, Malatya, Turkey.
Am J Cardiol. 2004 Nov 15;94(10):1303-6. doi: 10.1016/j.amjcard.2004.07.120.
This study evaluated plasma C-reactive protein (CRP) levels, a specific marker of inflammation, in 32 patients with isolated coronary artery ectasia (CAE) and compared the results with those of 32 patients with obstructive coronary artery disease without coronary artery ectasia and 30 subjects with angiographically normal coronary arteries. CRP levels were found to be significantly higher in patients with isolated CAE (p <0.001), suggesting that more severe inflammation may be involved in the pathogenesis of CAE.
本研究评估了32例孤立性冠状动脉扩张(CAE)患者的血浆C反应蛋白(CRP)水平(一种炎症的特异性标志物),并将结果与32例无冠状动脉扩张的阻塞性冠状动脉疾病患者以及30例冠状动脉造影正常的受试者进行了比较。结果发现,孤立性CAE患者的CRP水平显著更高(p<0.001),这表明更严重的炎症可能参与了CAE的发病机制。