丘脑底核的深部脑刺激可降低抗帕金森病药物成本。
Deep brain stimulation of the subthalamic nucleus reduces antiparkinsonian medication costs.
作者信息
Charles P David, Padaliya Bimal B, Newman William J, Gill Chandler E, Covington Cassondra D, Fang John Y, So Stephanie A, Tramontana Michael G, Konrad Peter E, Davis Thomas L
机构信息
The Movement Disorders Clinic, Department of Neurology, Vanderbilt University Medical Center, 2100 Pierce Avenue, Suite 352 MCS, Vanderbilt University, Nashville, TN 37212-3375, USA.
出版信息
Parkinsonism Relat Disord. 2004 Dec;10(8):475-9. doi: 10.1016/j.parkreldis.2004.05.006.
This study reports a retrospective analysis of 16 patients to determine changes in medication costs associated with deep brain stimulation of the bilateral subthalamic nucleus (DBS B-STN). Antiparkinsonian medication (APMED) costs were evaluated pre- and post-operatively at 1 and 2 years, based on prescribed dosages. After treatment with DBS, patients experienced a 32% reduction in APMED costs after 1 year and a 39% reduction after 2 years. Hypothetical projections of total potential savings are presented, accounting for increasingly complex medication regimens and medication cost inflation. DBS patients may experience a significant long-term reduction in the cost of their pharmacologic treatment.
本研究报告了对16例患者的回顾性分析，以确定与双侧丘脑底核深部脑刺激术（DBS B-STN）相关的药物成本变化。根据规定剂量，在术前以及术后1年和2年评估抗帕金森药物（APMED）成本。接受DBS治疗后，患者在1年后APMED成本降低了32%，在2年后降低了39%。文中给出了考虑到日益复杂的药物治疗方案和药物成本上涨的潜在总节省的假设预测。DBS患者可能会在长期内显著降低其药物治疗成本。
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