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RNA degradation induced by the herpes simplex virus vhs protein proceeds 5' to 3' in vitro.
J Virol. 2004 Dec;78(23):13391-4. doi: 10.1128/JVI.78.23.13391-13394.2004.
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The pseudorabies virus vhs protein cleaves RNA containing an IRES sequence.
FEBS J. 2016 Mar;283(5):899-911. doi: 10.1111/febs.13642. Epub 2016 Feb 3.
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Herpes simplex virus infection stabilizes cellular IEX-1 mRNA.
J Virol. 2005 Apr;79(7):4090-8. doi: 10.1128/JVI.79.7.4090-4098.2005.

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ADAR1 p150 prevents HSV-1 from triggering PKR/eIF2α-mediated translational arrest and is required for efficient viral replication.
PLoS Pathog. 2025 Apr 8;21(4):e1012452. doi: 10.1371/journal.ppat.1012452. eCollection 2025 Apr.
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Multiple Posttranscriptional Strategies To Regulate the Herpes Simplex Virus 1 vhs Endoribonuclease.
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Selective degradation of mRNAs by the HSV host shutoff RNase is regulated by the UL47 tegument protein.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):E1669-75. doi: 10.1073/pnas.1305475110. Epub 2013 Apr 15.
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Evidence for translational regulation by the herpes simplex virus virion host shutoff protein.
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The herpes simplex virus 1 UL41 gene-dependent destabilization of cellular RNAs is selective and may be sequence-specific.
Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3603-8. doi: 10.1073/pnas.0400354101. Epub 2004 Mar 1.
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Herpes simplex virus virion host shutoff protein: immune evasion mediated by a viral RNase?
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Pathogenesis of herpes simplex virus type 2 virion host shutoff (vhs) mutants.
J Virol. 2002 Mar;76(5):2054-61. doi: 10.1128/jvi.76.5.2054-2061.2002.
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Herpes simplex virus vhs protein.
Methods Enzymol. 2001;342:440-51. doi: 10.1016/s0076-6879(01)42565-1.

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