Nawrot Tim S, Hoppenbrouwers Karel, Den Hond Elly, Fagard Robert H, Staessen Jan A
Studiecoördinatiecentrum, Hypertensie en Cardiovasculaire Revalidatie Eenheid, Departement Moleculair en Cardiovasculair Onderzoek, Katholieke Universiteit Leuven, Faculteit Geneeskunde, Leuven, Belgium.
Eur J Public Health. 2004 Dec;14(4):361-5. doi: 10.1093/eurpub/14.4.361.
Risk factors in young adulthood may persist into later life and eventually lead to cardiovascular (CV) disease. The purpose of this study was to describe the prevalence of hypertension and other established CV risk factors in older adolescents.
Study nurses examined 120 girls and 80 boys with a mean age of 17.4 (SD, 0.8; range 15.8-19.6 years). After 5 minutes of sitting rest, resting blood pressure (BP) of the participants was measured in triplicate by sphygmomanometry. Body height and weight were measured and body mass index (BMI) was calculated. Serum lipids, smoking and drinking status were assessed. Hypertension was diagnosed according to the criteria specified in the 1996 update of the Task Force on BP treatment in Children and Adolescents (Pediatrics 1996;98:649-58).
Almost 25% of the subjects currently smoked with a median daily consumption of 6 (Interquartile 4-9) and 11 (6-16) cigarettes in girls and boys, respectively. Fourty-nine (41%) girls used oral contraceptives. Systolic (118 versus 109 mm Hg, p<0.001) and diastolic BPs (70.5 versus 68.0 mm Hg, p=0.033) were significantly higher in boys than in girls. Two (2%) girls and four (5%) boys had systolic hypertension; diastolic hypertension was found in six (5%) girls and one (1%) boy. Twelve (10%) girls and six (8%) boys were overweight (>25.0 kg/m2). Twenty (17%) girls and seven (9%) boys had hypercholesterolemia (total serum cholesterol > or =5.2 mmol/L). Overall, 50 (42%) girls and 31 (39%) boys had at least one CV risk factor, 12 (10%) girls and four (5%) boys had two risk factors, and three (3%) girls and one (1%) boy had more than two risk factors.
In 17-year-olds living in an affluent society the prevalence of CV risk factors was high. These findings underscore the importance of health education and prevention at this age.
青年期的风险因素可能持续到晚年,并最终导致心血管疾病。本研究的目的是描述大龄青少年高血压及其他已确定的心血管风险因素的患病率。
研究护士检查了120名女孩和80名男孩,平均年龄为17.4岁(标准差0.8;范围15.8 - 19.6岁)。在静坐休息5分钟后,使用血压计对参与者的静息血压进行三次测量。测量身高和体重并计算体重指数(BMI)。评估血脂、吸烟和饮酒状况。根据1996年更新的儿童和青少年血压治疗工作组标准(《儿科学》1996年;98:649 - 58)诊断高血压。
近25%的受试者目前吸烟,女孩和男孩的日均吸烟量中位数分别为6支(四分位间距4 - 9支)和11支(6 - 16支)。49名(41%)女孩使用口服避孕药。男孩的收缩压(118对109 mmHg,p<0.001)和舒张压(70.5对68.0 mmHg,p = 0.033)显著高于女孩。2名(2%)女孩和4名(5%)男孩患有收缩期高血压;6名(5%)女孩和1名(1%)男孩患有舒张期高血压。12名(10%)女孩和6名(8%)男孩超重(>25.0 kg/m²)。20名(17%)女孩和7名(9%)男孩患有高胆固醇血症(血清总胆固醇≥5.2 mmol/L)。总体而言,50名(42%)女孩和31名(39%)男孩至少有一项心血管风险因素,12名(10%)女孩和4名(5%)男孩有两项风险因素,3名(3%)女孩和1名(1%)男孩有两项以上风险因素。
在生活富裕社会的17岁青少年中,心血管风险因素的患病率很高。这些发现强调了这个年龄段健康教育和预防的重要性。