Campos Fábio Guilherme, Leite Andrea Furlan, Araújo Sérgio Eduardo Alonso, Atuí Fábio César, Seid Vítor, Habr-Gama Angelita, Kiss Desidério Roberto, Gama-Rodrigues Joaquim
Department of Gastroenterology, Coloproctology Unit, Hospital das Clínicas, Faculty of Medicine, University of São Paulo - São Paulo/SP, Brazil.
Rev Hosp Clin Fac Med Sao Paulo. 2004 Oct;59(5):296-301. doi: 10.1590/s0041-87812004000500013. Epub 2004 Oct 29.
Gastrointestinal mesenchymal tumors comprise a rare group of gastrointestinal tract wall tumors that have long been a source of confusion and controversy, especially in terms of pathological classification, preoperative diagnosis, management strategies, and prognosis. This report describes the clinical manifestations and management of 2 rectal leiomyomas and reviews the pertinent literature. Case 1: A 44-year-old woman was admitted reporting a nodule in the right para-anal region for the previous 2 years. At proctological examination, a 4-cm diameter fibrous mass situated in the para-anal region that produced an arch under the smooth muscle on the right rectal wall just above the anorectal ring was noted. Computed tomography and magnetic resonance imaging of the abdomen and pelvis showed the lesion and detected no other abnormalities. Surgical treatment consisted of wide local resection of the tumor through a para-anal incision, with no attempts to perform lymphadenectomy. Case 2: A 40-year-old male patient was admitted reporting constant anal pain for 4 months. He presented a 3-cm submucosal nodule at the anterior rectal wall just above the dentate line. After 2 inconclusive preoperative biopsies, transanal resection of the tumor was performed. Histological analysis of the specimen showed a benign leiomyoma. A review of the literature is presented, emphasizing some clinical and therapeutic aspects of this unusual rectal tumor.
胃肠道间质瘤是一组罕见的胃肠道壁肿瘤,长期以来一直是困惑和争议的根源,尤其是在病理分类、术前诊断、治疗策略和预后方面。本报告描述了2例直肠平滑肌瘤的临床表现和治疗方法,并回顾了相关文献。病例1:一名44岁女性因右肛门旁区域有一结节2年入院。直肠检查时,发现肛门旁区域有一个直径4厘米的纤维性肿块,该肿块在肛门直肠环上方右侧直肠壁平滑肌下形成一个弓形。腹部和盆腔的计算机断层扫描和磁共振成像显示了病变,未发现其他异常。手术治疗包括通过肛门旁切口对肿瘤进行广泛局部切除,未尝试进行淋巴结清扫。病例2:一名40岁男性患者因持续肛门疼痛4个月入院。他在齿状线以上的直肠前壁有一个3厘米的黏膜下结节。在两次术前活检结果不明确后,对肿瘤进行了经肛门切除。标本的组织学分析显示为良性平滑肌瘤。本文对文献进行了综述,强调了这种不寻常直肠肿瘤的一些临床和治疗方面。