Pillsbury H C, Pulver S, Carrasco V N, Scruggs K, Carver D, de Serres L, Bleynat M, Prazma J
Division of Otolaryngology/Head and Neck Surgery, University of North Carolina, Chapel Hill 27599-7070.
Arch Otolaryngol Head Neck Surg. 1992 Apr;118(4):413-6. doi: 10.1001/archotol.1992.01880040079013.
The autonomic innervation of the inner ear has been investigated earlier, yet questions concerning the origin, function, extent, and distribution of sympathetic nerves in the cochlea still remain unanswered. This study investigates the extent and distribution of adrenergic nerves in the cochlea. Our procedure combines the glyoxylic acid method of catecholamine fluorophore identification with rapid dissection, decalcification, and whole-mount slide preparation techniques to topographically trace the adrenergic innervation of the cochlear infrastructure. We have demonstrated that perivascular adrenergic innervation extends beyond the immediate branches of the modiolar artery and reaches into radiating arterioles. These findings also suggest the possibility of segmental regulation of cochlear blood flow.
内耳的自主神经支配已在早期进行了研究，但关于耳蜗交感神经的起源、功能、范围和分布的问题仍未得到解答。本研究调查了耳蜗中肾上腺素能神经的范围和分布。我们的方法将儿茶酚胺荧光团鉴定的乙醛酸法与快速解剖、脱钙和整装玻片制备技术相结合，以从地形学上追踪耳蜗结构的肾上腺素能神经支配。我们已经证明，血管周围的肾上腺素能神经支配超出了蜗轴动脉的直接分支，并延伸到放射状小动脉。这些发现也提示了耳蜗血流节段性调节的可能性。
