Raguse J D, Gath H J
Clinic for Oral and Maxillofacial Surgery, Charité University Clinic, Augustenburgerplatz 1, 13353 Berlin, Germany.
Br J Plast Surg. 2004 Dec;57(8):764-8. doi: 10.1016/j.bjps.2004.05.003.
The buccal fad pad flap (BFPF) is an easy to raise pedicled flap for closure of intraoral defects with barely any donor defect. The major disadvantage of the BFPF is the missing epithelial lining, which can induce fibrous tissue formation with resulting functional impairment. To overcome this problem we lined the BFPF with a dermal replacement (Dermagraft) consisting of living metabolic active fibroblasts. In six patients, defects resulting from tumour removal were reconstructed with a combination of the BFPF and Dermagraft and followed up for at least 2 years. In all patients a defect closure was achieved with no functional impairment. The clinical character which was achieved was more a type of defect regeneration than a flap closure. The availability of bioengineered metabolic active tissue can overcome the major problem of the BFPF as an option for defect closure of the buccal side. Furthermore the regeneration of the defects optimises clinical tumour monitoring.
颊脂垫瓣（BFPF）是一种易于掀起的带蒂瓣，用于关闭口腔内缺损，几乎不会留下供区缺损。BFPF的主要缺点是缺少上皮衬里，这会导致纤维组织形成，从而造成功能障碍。为克服这一问题，我们用一种由具有代谢活性的活成纤维细胞组成的真皮替代物（Dermagraft）覆盖BFPF。对6例因肿瘤切除导致缺损的患者，采用BFPF与Dermagraft联合进行修复，并随访至少2年。所有患者均实现缺损关闭，且无功能障碍。所实现的临床特征更像是一种缺损再生而非皮瓣关闭。生物工程代谢活性组织的可用性可以克服BFPF作为颊侧缺损关闭选择时的主要问题。此外，缺损的再生优化了临床肿瘤监测。
