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利用高分辨率磁共振成像评估关节软骨修复组织的相关参数定义。

Definition of pertinent parameters for the evaluation of articular cartilage repair tissue with high-resolution magnetic resonance imaging.

作者信息

Marlovits Stefan, Striessnig Gabriele, Resinger Christoph T, Aldrian Silke M, Vecsei Vilmos, Imhof Herwig, Trattnig Siegfried

机构信息

Department of Traumatology, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.

出版信息

Eur J Radiol. 2004 Dec;52(3):310-9. doi: 10.1016/j.ejrad.2004.03.014.

DOI:10.1016/j.ejrad.2004.03.014
PMID:15544911
Abstract

To evaluate articular cartilage repair tissue after biological cartilage repair, we propose a new technique of non-invasive, high-resolution magnetic resonance imaging (MRI) and define a new classification system. For the definition of pertinent variables the repair tissue of 45 patients treated with three different techniques for cartilage repair (microfracture, autologous osteochondral transplantation, and autologous chondrocyte transplantation) was analyzed 6 and 12 months after the procedure. High-resolution imaging was obtained with a surface phased array coil placed over the knee compartment of interest and adapted sequences were used on a 1 T MRI scanner. The analysis of the repair tissue included the definition and rating of nine pertinent variables: the degree of filling of the defect, the integration to the border zone, the description of the surface and structure, the signal intensity, the status of the subchondral lamina and subchondral bone, the appearance of adhesions and the presence of synovitis. High-resolution MRI, using a surface phased array coil and specific sequences, can be used on every standard 1 or 1.5 T MRI scanner according to the in-house standard protocols for knee imaging in patients who have had cartilage repair procedures without substantially prolonging the total imaging time. The new classification and grading system allows a subtle description and suitable assessment of the articular cartilage repair tissue.

摘要

为了评估生物软骨修复后的关节软骨修复组织,我们提出了一种非侵入性、高分辨率磁共振成像(MRI)新技术,并定义了一种新的分类系统。为了定义相关变量,对45例采用三种不同软骨修复技术(微骨折、自体骨软骨移植和自体软骨细胞移植)治疗的患者在术后6个月和12个月时的修复组织进行了分析。使用置于感兴趣膝关节腔上方的表面相控阵线圈获得高分辨率图像,并在1 T MRI扫描仪上使用适配序列。对修复组织的分析包括九个相关变量的定义和评级:缺损填充程度、与边缘区的整合情况、表面和结构描述、信号强度、软骨下板层和软骨下骨状态、粘连外观以及滑膜炎的存在情况。根据机构内部膝关节成像标准方案,使用表面相控阵线圈和特定序列的高分辨率MRI可用于每台标准1 T或1.5 T MRI扫描仪,用于对接受软骨修复手术的患者进行成像,且不会大幅延长总成像时间。新的分类和分级系统能够对关节软骨修复组织进行细致描述和恰当评估。

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