Downs Amr
South West Laser Centre, Exeter Nuffield, Exeter, UK. Anthony.Downs@rdehc tr.swest.nhs.uk
J Cosmet Laser Ther. 2004 Nov;6(3):163-4. doi: 10.1080/14764170410003002.
The attributes of the Smoothbeam laser--a 1450 nm diode laser--were considered likely to improve two distinct chronic conditions of flexural skin: Hailey-Hailey disease (HHD) and hidradenitis suppurativa (HS).
A series of laser treatments were given to the axillae of one patient with each condition.
Treatments were painful but tolerated. There were no adverse sequelae following laser treatment. For the patient with HS, partial improvement was achieved after four treatments and sweating was notably reduced. Intermittent laser treatment may be needed to maintain or build upon the improvements gained. Longstanding HS cases, however, with established sinuses and thick scar tissue are unlikely to be helped by this form of laser treatment. There was no subjective or objective improvement seen in the patient with HHD. The only notable beneficial effect was a marked reduction in sweating and elimination of the malodour.
Subsurfacing laser treatment in contrast with resurfacing laser treatment has no benefit in the management of HHD. Why the Smoothbeam laser causes sweat reduction is not known--and its clinical value has yet to be established.
Smoothbeam激光（一种1450纳米二极管激光）的特性被认为可能改善两种不同的弯曲皮肤慢性病症：黑汗病（HHD）和化脓性汗腺炎（HS）。
对一名患有每种病症的患者的腋窝进行了一系列激光治疗。
治疗过程有疼痛感但可耐受。激光治疗后未出现不良后遗症。对于患有HS的患者，四次治疗后取得了部分改善，出汗明显减少。可能需要间歇性激光治疗以维持或巩固所取得的改善。然而，对于长期存在且已形成窦道和厚瘢痕组织的HS病例，这种形式的激光治疗不太可能有帮助。患有HHD的患者未出现主观或客观改善。唯一显著的有益效果是出汗明显减少且异味消除。
与表面重塑激光治疗相比，皮下激光治疗对HHD的治疗没有益处。尚不清楚Smoothbeam激光为何会导致出汗减少，其临床价值尚未确立。
