Inelmen E M, Toffanello E D, Enzi G, Gasparini G, Miotto F, Sergi G, Busetto L
Department of Medical and Surgical Science, Division of Geriatrics, University of Padua, Italy.
Int J Obes (Lond). 2005 Jan;29(1):122-8. doi: 10.1038/sj.ijo.0802846.
To investigate the impact on drop-out rates of several baseline clinical characteristics of a sample of overweight and obese outpatients.
Retrospective clinical trial.
The charts of 383 patients aged 15-82 y attending an outpatient clinic for the treatment of obesity were examined from the first clinical evaluation until 1 y of diet ambulatory treatment.
We characterised the participants at baseline on the basis of their somatic characteristics, socioeconomic status, obesity-related diseases and dietary habits. The most significant factors resulting in univariate statistical analysis (waist, body mass index (BMI), full-time job, depressive syndrome, number of obesity-related diseases, daily frequency of fruit consumption) were then examined as independent variables in direct multiple logistic regression with the dependent variable drop-out.
The 1-y drop-out rate was 77.3%. A total of 87 patients completed the follow-up study. The noncompleter patients had slightly lower BMI and waist circumference mean values, and they were further regularly employed in full-time jobs, while the completer patients were principally pensioners and housewives. Drop-outs had a lower number of obesity-related diseases and as a result were less depressed. By the logistic regression, full-time job is the best predictor of premature withdrawal (odds ratio=2.40). Age, gender, anthropometric measurements, lifestyle and dietary habits did not result as significant predictors of drop-out.
The overweight and obese outpatients at higher risk of ambulatory treatment drop-out are more likely to work full hours, have less obesity-related complications and be less depressed. In our study, the full-time job condition seems to be the strongest predictor of premature withdrawal.
研究超重和肥胖门诊患者的几个基线临床特征对退出率的影响。
回顾性临床试验。
对383例年龄在15 - 82岁、前往门诊治疗肥胖症的患者病历进行检查,从首次临床评估直至为期1年的饮食门诊治疗结束。
我们根据参与者的身体特征、社会经济状况、肥胖相关疾病和饮食习惯对其基线特征进行描述。然后,在单变量统计分析中产生的最显著因素(腰围、体重指数(BMI)、全职工作、抑郁综合征、肥胖相关疾病数量、每日水果食用频率)作为自变量,以退出作为因变量进行直接多元逻辑回归分析。
1年的退出率为77.3%。共有87例患者完成了随访研究。未完成研究的患者BMI和腰围平均值略低,且更多从事全职工作,而完成研究的患者主要是退休人员和家庭主妇。退出者患肥胖相关疾病的数量较少,因此抑郁程度也较低。通过逻辑回归分析,全职工作是提前退出的最佳预测因素(比值比 = 2.40)。年龄、性别、人体测量指标、生活方式和饮食习惯并非退出的显著预测因素。
门诊治疗退出风险较高的超重和肥胖门诊患者更有可能全职工作,肥胖相关并发症较少,抑郁程度较低。在我们的研究中,全职工作状况似乎是提前退出的最强预测因素。