Tao Houchao, Hwang Inkyu, Boger Dale L
Department of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
Bioorg Med Chem Lett. 2004 Dec 20;14(24):5979-81. doi: 10.1016/j.bmcl.2004.10.002.
A series of amide derivatives of permethyl ningalin B were prepared and examined as multidrug resistance (MDR) reversal agents illustrating that the C5 carboxylate is widely tolerant of such derivatization.
制备了一系列全甲基宁甘林B的酰胺衍生物，并将其作为多药耐药（MDR）逆转剂进行研究，结果表明C5羧酸盐对这种衍生化具有广泛的耐受性。
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