Zapor Michael J, Cozza Kelly L, Wynn Gary H, Wortmann Glenn W, Armstrong Scott C
Department of Medicine, Walter Reed Army Medical Center, Uniformed Services University of the Health Sciences, F. Edward Herbert School of Medicine, Bethesda, MD, USA.
Psychosomatics. 2004 Nov-Dec;45(6):524-35. doi: 10.1176/appi.psy.45.6.524.
The second in a series reviewing the HIV/AIDS antiretroviral drugs. This review summarizes the non-protease inhibitor antiretrovirals: nucleoside and nucleotide analogue reverse transcriptase inhibitors (NRTIs), the nonnucleoside reverse transcriptase inhibitors (NNRTIs), and cell membrane fusion inhibitors. In an overview format for primary care physicians and psychiatrists, this review presents the mechanism of action, side effects, toxicities, and drug interactions of these agents.
这是关于艾滋病抗逆转录病毒药物系列综述中的第二篇。本综述总结了非蛋白酶抑制剂类抗逆转录病毒药物:核苷及核苷酸类似物逆转录酶抑制剂(NRTIs)、非核苷逆转录酶抑制剂(NNRTIs)以及细胞膜融合抑制剂。以概述形式为初级保健医生和精神科医生呈现这些药物的作用机制、副作用、毒性及药物相互作用。