Flory W, Spainhour C B, Colvin B, Herbert C D
Department of Veterinary Anatomy and Public Health, College of Veterinary Medicine, Texas A&M University, College Station 77843.
J Vet Diagn Invest. 1992 Jan;4(1):65-9. doi: 10.1177/104063879200400114.
Feed grain suspected of causing death in a group of pigs was evaluated for toxic potential in chickens. The contaminated grain sorghum mixture was examined visually and contained 3.7% Cassia occidentalis and 1.6% Cassia obtusifolia seeds by weight. Thirty-two chicks were fed a sample of this suspect grain sorghum mixture. Chickens receiving the contaminated grain lost weight rapidly, exhibited clinical signs typical of intoxication with Cassia spp., and by day 16 were severely debilitated. Necropsy and histologic and electron microscopic examinations demonstrated a skeletal and cardiac degenerative myopathy consistent with intoxication by Cassia occidentalis. These toxicologic investigations verified the toxic potential of the contaminated sorghum mixture for chickens, and these comparative observations support prior diagnostic efforts implicating Cassia spp. as a cause of illness in swine.
对疑似导致一群猪死亡的饲料谷物进行了鸡的毒性潜力评估。对受污染的谷物高粱混合物进行了外观检查，按重量计含有3.7%的望江南种子和1.6%的决明子种子。给32只雏鸡喂食了这种可疑谷物高粱混合物的样本。食用受污染谷物的鸡体重迅速减轻，表现出典型的决明属植物中毒临床症状，到第16天严重虚弱。尸检以及组织学和电子显微镜检查显示，存在与望江南中毒相符的骨骼肌和心肌退行性肌病。这些毒理学研究证实了受污染高粱混合物对鸡的毒性潜力，这些比较观察结果支持了先前将决明属植物作为猪疾病病因的诊断工作。
