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鼻软骨间叶性错构瘤:1例报告及文献复习

Nasal chondromesenchymal hamartoma: report of a case and review of the literature.

作者信息

Norman Elizabeth S, Bergman Simon, Trupiano Jacqueline K

机构信息

Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.

出版信息

Pediatr Dev Pathol. 2004 Sep-Oct;7(5):517-20. doi: 10.1007/s10024-004-1003-2. Epub 2004 Jul 30.

Abstract

The sinonasal region is the site of several hamartomatous lesions, the majority of which are mesenchymal, with vascular hamartomas predominating. The occurrence of hamartomas in the nasal cavity of infants and children is especially rare. Nasal chondromesenchymal hamartoma (NCMH) is a rare lesion of the intranasal sinuses generally diagnosed in the newborn period, with the eldest reported patient presenting at 16 years of age. This neoplasm is composed of mesenchymal-stromal and chondroid tissue in varying proportions. It is felt to be analogous to the mesenchymal hamartoma of the chest wall, a lesion of similar histology generally involving the ribs and chest wall of neonates. To the best of our knowledge, only 14 cases of NCMH have been reported to date. We report a case of NCMH in an 11-year-old boy.

摘要

鼻窦区域是几种错构瘤性病变的发生部位,其中大多数为间叶性病变,以血管错构瘤为主。错构瘤在婴幼儿鼻腔中尤为罕见。鼻软骨间叶错构瘤(NCMH)是一种罕见的鼻窦内病变,通常在新生儿期被诊断出来,报道的年龄最大的患者为16岁。这种肿瘤由不同比例的间叶基质组织和软骨样组织组成。它被认为类似于胸壁间叶错构瘤,这是一种组织学相似的病变,通常累及新生儿的肋骨和胸壁。据我们所知,迄今为止仅报道了14例NCMH。我们报告了一例11岁男孩的NCMH病例。

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