Vijayasundaram S, Gopalakrishnan S, Karthikeyan P, Vignesh R
Department of Otorhinolaryngology and Head and Neck Surgery, Mahatma Gandhi Medical College and Research Institute, Pondicherry, India.
Indian J Otolaryngol Head Neck Surg. 2022 Oct;74(Suppl 2):1253-1255. doi: 10.1007/s12070-020-02333-7. Epub 2021 Jan 7.
Nasal chondromesenchymal hamartoma (NCMH) is a rare benign lesion of the sinonasal tract in children and adolescent with orbital involvement. NCMH is histologically composed of nodules of cartilage with cellular density variation and maturation of the chondrocytes, a myxoid to spindle cell stroma, focal osteoclast-like giant cells in the stroma, and erythrocyte-filled spaces. This lesion may present with a destructive pattern on imaging, highly suggestive of malignancy. Total endoscopic resection is the choice of treatment nowadays, however incomplete excision could result in tumor recurrence but rare.
鼻软骨间叶性错构瘤(NCMH)是一种发生于儿童和青少年鼻窦道的罕见良性病变,可累及眼眶。NCMH在组织学上由软骨结节组成,软骨细胞的细胞密度存在差异且有成熟过程,有黏液样至梭形细胞基质、基质中局灶性破骨细胞样巨细胞以及充满红细胞的间隙。该病变在影像学上可能呈现出侵袭性表现,高度提示为恶性肿瘤。如今,全内镜切除术是首选的治疗方法,然而切除不完全可能导致肿瘤复发,但这种情况较为罕见。