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鼻软骨间叶性错构瘤:成年女性中的一种罕见良性病变。

Nasal Chondromesenchymal Hamartoma: A Rare Benign Lesion in Adult Female.

作者信息

Vijayasundaram S, Gopalakrishnan S, Karthikeyan P, Vignesh R

机构信息

Department of Otorhinolaryngology and Head and Neck Surgery, Mahatma Gandhi Medical College and Research Institute, Pondicherry, India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2022 Oct;74(Suppl 2):1253-1255. doi: 10.1007/s12070-020-02333-7. Epub 2021 Jan 7.

DOI:10.1007/s12070-020-02333-7
PMID:33437683
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7790346/
Abstract

Nasal chondromesenchymal hamartoma (NCMH) is a rare benign lesion of the sinonasal tract in children and adolescent with orbital involvement. NCMH is histologically composed of nodules of cartilage with cellular density variation and maturation of the chondrocytes, a myxoid to spindle cell stroma, focal osteoclast-like giant cells in the stroma, and erythrocyte-filled spaces. This lesion may present with a destructive pattern on imaging, highly suggestive of malignancy. Total endoscopic resection is the choice of treatment nowadays, however incomplete excision could result in tumor recurrence but rare.

摘要

鼻软骨间叶性错构瘤(NCMH)是一种发生于儿童和青少年鼻窦道的罕见良性病变,可累及眼眶。NCMH在组织学上由软骨结节组成,软骨细胞的细胞密度存在差异且有成熟过程,有黏液样至梭形细胞基质、基质中局灶性破骨细胞样巨细胞以及充满红细胞的间隙。该病变在影像学上可能呈现出侵袭性表现,高度提示为恶性肿瘤。如今,全内镜切除术是首选的治疗方法,然而切除不完全可能导致肿瘤复发,但这种情况较为罕见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8809/9702403/de613e833c37/12070_2020_2333_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8809/9702403/e09fe46b4174/12070_2020_2333_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8809/9702403/7649086cf1e8/12070_2020_2333_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8809/9702403/19c40d999c6e/12070_2020_2333_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8809/9702403/de613e833c37/12070_2020_2333_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8809/9702403/e09fe46b4174/12070_2020_2333_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8809/9702403/7649086cf1e8/12070_2020_2333_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8809/9702403/19c40d999c6e/12070_2020_2333_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8809/9702403/de613e833c37/12070_2020_2333_Fig4_HTML.jpg

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引用本文的文献

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BMJ Case Rep. 2023 Nov 15;16(11):e254457. doi: 10.1136/bcr-2022-254457.
2
A Systematic Review of Nasal Chondromesenchymal Hamartoma (NCMH) with a New Case Report.鼻腔软骨黏液样错构瘤(Nasal Chondromesenchymal Hamartoma,NCMH)的系统评价附 1 例新病例报告。
Head Neck Pathol. 2022 Dec;16(4):1172-1184. doi: 10.1007/s12105-022-01452-7. Epub 2022 May 4.

本文引用的文献

1
Endoscopic endonasal excision of nasal chondromesenchymal hamartoma with intracranial extension.内镜经鼻颅内外沟通鼻软骨黏液样软骨瘤切除术。
Eur Ann Otorhinolaryngol Head Neck Dis. 2017 Dec;134(6):423-425. doi: 10.1016/j.anorl.2016.05.014. Epub 2017 Apr 25.
2
Nasal chondromesenchymal hamartoma: radiographic and histopathologic analysis of a rare pediatric tumor.鼻软骨间叶性错构瘤:一种罕见儿童肿瘤的影像学和组织病理学分析
Pediatr Radiol. 2007 Jan;37(1):101-4. doi: 10.1007/s00247-006-0352-6. Epub 2006 Nov 8.
3
Nasal chondromesenchymal hamartoma in older children and adults: series and immunohistochemical analysis.
大龄儿童及成人的鼻软骨间叶性错构瘤:病例系列及免疫组化分析
Arch Pathol Lab Med. 2005 Nov;129(11):1444-50. doi: 10.5858/2005-129-1444-NCHIOC.
4
Nasal chondromesenchymal hamartoma: report of a case and review of the literature.鼻软骨间叶性错构瘤:1例报告及文献复习
Pediatr Dev Pathol. 2004 Sep-Oct;7(5):517-20. doi: 10.1007/s10024-004-1003-2. Epub 2004 Jul 30.
5
Mesenchymal chondrosarcoma of the sinonasal tract: a clinicopathological study of 13 cases with a review of the literature.鼻窦间叶性软骨肉瘤:13例临床病理研究并文献复习
Laryngoscope. 2003 May;113(5):783-90. doi: 10.1097/00005537-200305000-00004.
6
Nasal chondromesenchymal hamartoma: an upper respiratory tract analogue of the chest wall mesenchymal hamartoma.鼻软骨间叶性错构瘤:一种胸壁间叶性错构瘤的上呼吸道类似物。
Am J Surg Pathol. 1998 Apr;22(4):425-33. doi: 10.1097/00000478-199804000-00006.