Hirose Hitoshi, Amano Atsushi, Takahashi Akihito
Department of Cardiovascular Surgery, Shin-Tokyo Hospital, Chiba, Japan.
J Card Surg. 2004 Nov-Dec;19(6):499-504. doi: 10.1111/j.0886-0440.2004.04103.x.
We investigated the clinical outcomes after coronary artery bypass grafting (CABG) using the in situ gastroepiploic artery (GEA) exclusively bypassing to the distal right coronary artery (RCA).
Between, 1991 and 2002, 1020 consecutive patients (788 male and 232 female with a mean age of 63.6 +/- 9.7) underwent CABG to the distal coronary artery using in situ GEA in the Shin-Tokyo Hospital Group. Their perioperative and follow-up data were retrospectively analyzed.
The in-hospital morbidity rate was 15.1% and the mortality rate was 0.6%. Postoperative myocardial infarction associated with GEA graft failure occurred in two cases. Among the survivors, follow-up was completed in all patients with a mean period of 4.7 +/- 2.4 years. Actuarial 3- and 5-year angina or intervention-free rates were 93.6% and 89.9%, respectively. Actuarial 3- and 5-year survival rates were 95.8% and 91.6%, respectively. Postoperative angiography was performed on 482 patients within 1 year, 115 patients with 3 years, and in 87 patients more than 4 year after surgery. The GEA patency rates at 1, 3, and 5-year were 95.7%, 90.2%, and 85.7%, respectively. These patency rates were compared with other graft materials (the saphenous vein n = 291, radial artery n = 186, and right internal thoracic artery n = 23) used for bypass to the distal RCA, and we found no significant differences (p = 0.29).
The perioperative and clinical remote results of GEA grafting were satisfactory. The angiographic patency rates of GEA to the distal RCA was not inferior to the saphenous vein graft in this study.
我们研究了仅使用原位胃网膜动脉(GEA)搭桥至右冠状动脉(RCA)远端进行冠状动脉旁路移植术(CABG)后的临床结果。
1991年至2002年间,东京心脏医院集团的1020例连续患者(788例男性和232例女性,平均年龄63.6±9.7岁)接受了使用原位GEA搭桥至冠状动脉远端的CABG。对他们的围手术期和随访数据进行回顾性分析。
住院发病率为15.1%,死亡率为0.6%。2例发生了与GEA移植失败相关的术后心肌梗死。在幸存者中,所有患者均完成了随访,平均随访时间为4.7±2.4年。3年和5年无心绞痛或无需干预的精算率分别为93.6%和89.9%。3年和5年精算生存率分别为95.8%和91.6%。术后1年内对482例患者进行了血管造影,术后3年对115例患者进行了血管造影,术后4年以上对87例患者进行了血管造影。1年、3年和5年时GEA的通畅率分别为95.7%、90.2%和85.7%。将这些通畅率与用于搭桥至RCA远端的其他移植材料(大隐静脉 n = 291、桡动脉 n = 186和右胸廓内动脉 n = 23)进行比较,我们发现无显著差异(p = 0.29)。
GEA移植的围手术期和临床远期结果令人满意。在本研究中,GEA至RCA远端的血管造影通畅率不低于大隐静脉移植。