Lin Long-Yau, Wu Jian-Hong, Yang Chiong-Wu, Sheu Bor-Ching, Lin Ho-Hsiung
Department of Obstetrics and Gynecology, Chung-Shan Medical University, Taichung, Taiwan.
Int Urogynecol J Pelvic Floor Dysfunct. 2004 Nov-Dec;15(6):418-21; discussion 421. doi: 10.1007/s00192-004-1187-z. Epub 2004 Jun 4.
To elucidate the impact of radical hysterectomy upon the urodynamic findings of patients with cervical cancer, 20 patients with cervical cancer at stage IB to IIA who underwent radical hysterectomy were recruited. Each patient underwent a 20-min pad test and urodynamic study prior to and 3 months after radical hysterectomy. ANOVA, Bonferroni test and paired t -test were utilized for analysis. The mean age of the 20 patients was 50.2+/-8.7 years with a mean parity of 3.5+/-1.5. Four (20%) of the 20 cases revealed normal urodynamic findings preoperatively, and the urodynamic findings became abnormal after surgery. Comparing the urodynamic parameters of both bladder voiding and storage functions pre- and post-surgery, we found significant impairments postoperatively in all 20 cases. Our data demonstrate that abnormal urodynamic findings may pre-exist for some patients with cervical cancer prior to surgical treatment. These findings may worsen, and/or additional abnormal states may arise subsequent to radical hysterectomy.
为阐明根治性子宫切除术对宫颈癌患者尿动力学检查结果的影响，我们招募了20例IB至IIA期宫颈癌且接受了根治性子宫切除术的患者。每位患者在根治性子宫切除术之前及术后3个月均接受了20分钟的尿垫试验和尿动力学检查。采用方差分析、Bonferroni检验和配对t检验进行分析。这20例患者的平均年龄为50.2±8.7岁，平均产次为3.5±1.5。20例中有4例（20%）术前尿动力学检查结果正常，但术后尿动力学检查结果变为异常。比较手术前后膀胱排尿和储尿功能的尿动力学参数，我们发现所有20例患者术后均有明显损害。我们的数据表明，一些宫颈癌患者在手术治疗前可能已存在异常尿动力学检查结果。这些结果可能会恶化，和/或在根治性子宫切除术后可能会出现其他异常情况。
