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伊维菌素的发展历程——一个成功故事

The life and times of ivermectin - a success story.

作者信息

Omura Satoshi, Crump Andy

机构信息

Kitasato Institute, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8642, Japan.

出版信息

Nat Rev Microbiol. 2004 Dec;2(12):984-9. doi: 10.1038/nrmicro1048.

DOI:10.1038/nrmicro1048
PMID:15550944
Abstract

Since its introduction more than 20 years ago, ivermectin has proved to be one of the most successful therapeutic drugs in veterinary medicine, as well as the basis of one of the most successful public-health programmes of the past century. The drug arose from a unique international collaboration between the public and private sectors. The development process also incorporated the world's first and largest drug-donation programme and involved a unique association between governments, non-governmental organizations and industry. The drug is now being used, free of charge, in two global disease-elimination programmes that are benefiting millions of the world's poorest people.

摘要

自20多年前问世以来,伊维菌素已被证明是兽医学中最成功的治疗药物之一,也是上个世纪最成功的公共卫生项目之一的基础。这种药物源自公共部门与私营部门之间独特的国际合作。其研发过程还纳入了全球首个也是规模最大的药品捐赠项目,并涉及政府、非政府组织和企业之间独特的合作关系。目前,该药正免费用于两项全球疾病消除项目,使全球数百万最贫困人群受益。

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