Lee Kyu Ha, Min Yong Deuk, Choi Sang Zin, Kwon Hak Cheol, Cho Ock Ryun, Lee Kang Choon, Lee Kang Ro
College of Pharmacy, SungKyunKwan University, Suwon 440-746, Korea.
Arch Pharm Res. 2004 Oct;27(10):1016-9. doi: 10.1007/BF02975423.
The chromatographic separation of a methylene chloride extract of Artemisia rubripes led to the isolation of a new sesquiterpene lactone (3), together with four known compounds, a coumarin (2) and three terpenes (1, 4, and 5). Their structures were characterized to be 1beta,6alpha-dihydroxy-4(15)-eudesmene (1), scopoletin (2), 1alpha,4beta-dihydroxy-8alpha-acetoxy-guaia-2,10(14), 11(13)-triene-6,12-olide (3), 1alpha,4beta-dihydroxy-8alpha-acetoxy-guaia-2,9,11(13)-triene-6,12-olide (4), and beta-sitosterol-3-O-beta-D-glycoside (5) by spectroscopic means.
对红足蒿二氯甲烷提取物进行色谱分离，得到一种新的倍半萜内酯（3）以及四种已知化合物，一种香豆素（2）和三种萜类化合物（1、4和5）。通过光谱手段确定它们的结构分别为1β,6α-二羟基-4(15)-桉叶烯（1）、东莨菪素（2）、1α,4β-二羟基-8α-乙酰氧基-愈创木-2,10(14),11(13)-三烯-6,12-内酯（3）、1α,4β-二羟基-8α-乙酰氧基-愈创木-2,9,11(13)-三烯-6,12-内酯（4）和β-谷甾醇-3-O-β-D-糖苷（5）。
