Castiglia P, Mura I, Masia M D, Maida I, Solinas G, Muresu E
Istituto di Igiene e Medicina Preventiva, Università degli Studi di Sassari, Sassari, Italia.
Ann Ig. 2004 Jan-Apr;16(1-2):103-8.
A cross-sectional sero-epidemiological study was conducted on teen-agers in Northern Sardinia, a low risk population for Lyme borreliosis. The adjusted sero-prevalence estimate for Enzyme Linked Immunofluorescent Assay on 443 teen-agers (229 males and 214 females) was 6.1%. The females vs males Odds Ratio was 5.1 (CI95%: 2.1-12.8). The prevalence was associated with the family size (chi2 for trend: p=0.03); teenagers without cohabitants, except parents, had a five fold risk (CI95%: 1.2-20.7) of sero-positivity in comparison to those with wider families. No significant association was found with other socio-economical indices nor with pet-owning. In conclusion, positive Lyme serology is not common in Northern Sardinia, but further sero-epidemiological survey on at high-risk population (forestry workers, hunters, shepherds) are needed.
在撒丁岛北部的青少年中开展了一项横断面血清流行病学研究,该地区是莱姆病螺旋体病的低风险人群。对443名青少年(229名男性和214名女性)进行酶联免疫荧光测定的校正血清阳性率估计为6.1%。女性与男性的比值比为5.1(95%置信区间:2.1-12.8)。患病率与家庭规模有关(趋势卡方检验:p=0.03);与家庭成员较多的青少年相比,除父母外无同居者的青少年血清阳性风险高五倍(95%置信区间:1.2-20.7)。未发现与其他社会经济指标以及是否养宠物有显著关联。总之,莱姆病血清学阳性在撒丁岛北部并不常见,但需要对高危人群(林业工人、猎人、牧羊人)进一步开展血清流行病学调查。