1型神经纤维瘤病患儿的迟发性视路肿瘤
Late-onset optic pathway tumors in children with neurofibromatosis 1.
作者信息
Listernick R, Ferner R E, Piersall L, Sharif S, Gutmann D H, Charrow J
机构信息
Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
出版信息
Neurology. 2004 Nov 23;63(10):1944-6. doi: 10.1212/01.wnl.0000144341.16830.01.
Identification of new optic pathway tumors (OPTs) and progression of pre-existing OPTs in children with neurofibromatosis 1 (NF1) have been reported infrequently after age 6. The authors present eight children with NF1 (mean age 12.2 years) seen in three NF1 centers who had either late-onset (four of eight) or late-progressive (seven of eight) OPT. Continued monitoring of individuals with NF1 into adulthood for the development of OPTs and for progression of known OPTs is warranted.
据报道，6岁以后，1型神经纤维瘤病（NF1）患儿中新发视神经通路肿瘤（OPT）的识别及既往存在的OPT进展情况鲜有报道。本文作者介绍了在三个NF1中心就诊的8名NF1患儿（平均年龄12.2岁），他们患有迟发性（8例中的4例）或迟发性进展性（8例中的7例）OPT。有必要对NF1患者持续监测至成年，以观察OPT的发生及已知OPT的进展情况。
Zotero 插件