Zeid Janice Lasky
Division of Ophthalmology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States.
Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Front Surg. 2022 Sep 2;9:908573. doi: 10.3389/fsurg.2022.908573. eCollection 2022.
Clinical and diagnostic evaluation in the follow-up of optic glioma patients with neurofibromatosis type 1 (NF-1) can be difficult. Determining whether and when to provide treatment is a significant challenge in best managing these patients. Update on current information and future directions in management is included in this review.
NF-associated optic pathway gliomas (OPGs) present a significant management challenge with high stakes for visual outcomes. Monitoring vision and diagnostic tests are challenging in patients of a younger age. Regardless of whether few or many optic gliomas are encountered during clinical practice.
This review of optic gliomas-NF1-associated gliomas includes the current approach and knowledge of OPG-NF1 and future directions in OPG-NF1 management. This includes the ongoing Multicenter Natural History Study and other clinical trials and outcomes in NF-1 patients with OPG.
对1型神经纤维瘤病（NF-1）相关视神经胶质瘤患者进行随访时，临床和诊断评估可能会很困难。确定是否以及何时进行治疗是妥善管理这些患者的一项重大挑战。本综述纳入了当前管理信息及未来管理方向的最新内容。
与NF相关的视神经通路胶质瘤（OPG）对视觉预后影响重大，给管理带来了巨大挑战。对较年轻患者进行视力监测和诊断测试具有挑战性。无论在临床实践中遇到的视神经胶质瘤数量多少。
本对视神经胶质瘤——NF1相关胶质瘤的综述包括OPG-NF1的当前方法和知识以及OPG-NF1管理的未来方向。这包括正在进行的多中心自然病史研究以及其他针对患有OPG的NF-1患者的临床试验和结果。
