Al-Azzawi L M, Mirza K B
Department of Oral Pathology, College of Dentistry--University of Baghdad, Iraq.
Electromyogr Clin Neurophysiol. 2004 Oct-Nov;44(7):387-94.
An evaluation of the extent and mechanism of damage of the central nervous system in diabetes mellitus is of high value in current neurological research. Electrophysiological abnormalities are frequently present is completely asymatomatic diabetes mellitus (DM) patients. Limited data is available in the use of brainstem auditory evoked potential (BAEP) in DM.
Is to evaluate the efficacy of BAEP as a method useful in the diagnosis of subclinical damage of the central nervous system in DM.
67 diabetes and 32 healthy controls - age and sex matched - were chosen. The diabetes were of type I and II and more than or less than 10 years duration. The BAEP was elicited by using auditory stimulus by using Dantec Evomatic 4000 evoked potential machine. The latency of component response recored as waves I, III and V, interpeak latency (IPLs) I - III, I - V, III - V and amplitude of waves V.
The difference was highly significant in the increased latency of waves I, III and V, interpeak latency (IPLs) I - III, I - V, III - V and amplitude of waves V of each type of diabetes as compared to control. Comparison of the type and duration of diabetes between each other showed no significant difference.
BAEP recording can represent an objective, clinically useful and non invasive procedure to stress the early impairment both of the auditory nerve and of brainstem function.
评估糖尿病中枢神经系统损伤的程度和机制在当前神经学研究中具有很高的价值。电生理异常在完全无症状的糖尿病患者中经常出现。关于糖尿病患者使用脑干听觉诱发电位（BAEP）的数据有限。
评估BAEP作为诊断糖尿病中枢神经系统亚临床损伤有用方法的有效性。
选取67例糖尿病患者和32例年龄和性别匹配的健康对照者。糖尿病患者为I型和II型，病程超过或不足10年。使用丹泰克Evomatic 4000诱发电位仪通过听觉刺激引出BAEP。记录成分反应的潜伏期，即波I、III和V的潜伏期，峰间潜伏期（IPL）I - III、I - V、III - V以及波V的波幅。
与对照组相比，各型糖尿病患者波I、III和V的潜伏期延长、峰间潜伏期（IPL）I - III、I - V、III - V以及波V的波幅差异具有高度显著性。各型糖尿病之间在类型和病程方面的比较无显著差异。
BAEP记录可作为一种客观、临床有用且无创的方法，用于强调听觉神经和脑干功能的早期损伤。
