Chernonosov A A, Kuznetsov N A, Koval V V, Pyshnyi D V, Derkacheva N M, Lukyanets E A, Fedorova O S
Institute of Chemical Biology and Fundamental Medicine, Novosibirsk, Russia.
Nucleosides Nucleotides Nucleic Acids. 2004 Oct;23(6-7):983-7. doi: 10.1081/NCN-200026051.
Thermodynamics of interaction of phthalocyanine-oligonucleotide conjugates with single- and double-stranded DNA resulting in formation of duplexes and triplexes was measured by UV melting method. It was shown that a phthalocyanine moiety of conjugates stabilized the formation of duplexes and triplexes.
采用紫外熔解方法测定了酞菁-寡核苷酸缀合物与单链和双链DNA相互作用形成双链体和三链体的热力学。结果表明，缀合物的酞菁部分稳定了双链体和三链体的形成。
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