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关于外阴痛医生评分的可靠性和有效性及其亚型的判别效度

On the reliability and validity of physician ratings for vulvodynia and the discriminant validity of its subtypes.

作者信息

Masheb Robin M, Lozano Christine, Richman Susan, Minkin Mary Jane, Kerns Robert D

机构信息

Yale University School of Medicine, PO Box 208098, New Haven, CT 06520-8098, USA.

出版信息

Pain Med. 2004 Dec;5(4):349-58. doi: 10.1111/j.1526-4637.2004.04060.x.

Abstract

OBJECTIVE

This study aimed to test the reliability and validity of physician ratings in a broadly defined sample of women with vulvodynia and to examine the external validity of the vulvodynia subtypes.

DESIGN

Participants were 50 women who were independently diagnosed with vulvodynia by two study gynecologists. Physician ratings corresponding to Friedrich's three criteria for vulvar vestibulitis were taken at the two examinations. Each participant's diagnosis was subtyped as vulvar vestibulitis (VV) or dysesthetic vulvodynia (DV) based upon the physician ratings. Participants completed standardized measures of pain, sexual function, psychological function, and quality of life to examine the discriminant validity of the subtypes.

RESULTS

Test-retest reliability for the physician ratings of Friedrich's three criteria was stable for two of the three criteria (i.e., pain on attempted vaginal entry and tenderness to pressure localized within the vulvar vestibule). When these criteria were used to categorize participants as having VV or DV, the subtypes were not statistically different for measures used to examine the discriminant validity of the subtypes. While the distribution of patients changed when premenopausal state was added to the inclusion criteria for VV, the subtypes differed little on the outcome measures.

CONCLUSIONS

Findings from the present study suggest that physician ratings for Friedrich's criteria can be operationalized and found to be reliable and valid in a wide range of women with vulvodynia. The absence of differences between subtypes on measures of pain, sexual function, psychological function, and quality of life challenge the clinical significance of these subtypes and support the theory that vulvodynia represents a continuum of chronic vulvar pain rather than two distinct entities.

摘要

目的

本研究旨在测试在广泛定义的外阴痛女性样本中医生评级的可靠性和有效性,并检验外阴痛亚型的外部有效性。

设计

50名女性参与者由两名研究妇科医生独立诊断为外阴痛。在两次检查时获取对应弗里德里希外阴前庭炎三条标准的医生评级。根据医生评级,将每位参与者的诊断分为外阴前庭炎(VV)或感觉异常性外阴痛(DV)亚型。参与者完成疼痛、性功能、心理功能和生活质量的标准化测量,以检验亚型的判别效度。

结果

弗里德里希三条标准的医生评级重测信度在三条标准中的两条上是稳定的(即试图插入阴道时的疼痛和外阴前庭内局限性压痛)。当使用这些标准将参与者分类为患有VV或DV时,在用于检验亚型判别效度的测量中,亚型在统计学上没有差异。虽然将绝经前状态添加到VV的纳入标准时患者分布发生了变化,但在结局测量指标上亚型差异不大。

结论

本研究结果表明,弗里德里希标准的医生评级可以实施,并且在广泛的外阴痛女性中是可靠和有效的。在疼痛、性功能、心理功能和生活质量测量指标上亚型之间没有差异,这对这些亚型的临床意义提出了挑战,并支持外阴痛代表慢性外阴疼痛连续体而非两种不同实体的理论。

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