Awasthi R, Harmse D, Courtney D, Lyons C B A
Department of Histopathology, Derriford Hospital, Derriford Road, Plymouth PL6 8DH, UK.
J Clin Pathol. 2004 Dec;57(12):1329-30. doi: 10.1136/jcp.2004.020172.
Benign mixed tumour of the skin (chondroid syringoma) is an uncommon skin adnexal tumour, usually presenting as a slow growing solitary painless nodule. The morphological appearances are similar to those of a pleomorphic adenoma of the salivary gland. Hair matrix and sebaceous differentiation can be seen in some lesions. Focal ossification is a rare finding. This report presents a case of a similar tumour arising in the cheek of a 43 year old white man, showing extensive ossification. Clinical, radiological, and pathological correlation and diagnosis proved to be difficult preoperatively. Only two cases of a benign mixed tumour with pronounced ossification have been reported so far, both in Japanese patients. This is the first reported case seen in a white man. Awareness of these lesions will avoid potential diagnostic pitfalls.
皮肤良性混合瘤(软骨样汗管瘤)是一种罕见的皮肤附属器肿瘤,通常表现为生长缓慢的孤立性无痛结节。其形态学表现与涎腺多形性腺瘤相似。在一些病变中可见毛发基质和皮脂腺分化。局灶性骨化是一种罕见的表现。本报告介绍了一例发生在一名43岁白人男性脸颊的类似肿瘤,表现为广泛骨化。术前临床、影像学和病理的相关性及诊断颇具难度。迄今为止,仅报道过两例有明显骨化的良性混合瘤病例,均为日本患者。这是首例在白人中发现的此类病例。认识这些病变将避免潜在的诊断陷阱。