Akasaka T, Onodera H, Matsuta M
Department of Dermatology, School of Medicine, Iwate Medical University, Morioka, Japan.
J Dermatol. 1997 Feb;24(2):125-31. doi: 10.1111/j.1346-8138.1997.tb02757.x.
A 58-year-old Japanese male presented with a cutaneous mixed tumor containing ossification and hair matrix differentiation on the left side of the chin. Histologically, the tumor consisted almost exclusively of apocrine-type epithelial ductal structures and chondroid stroma. Strands and aggregation of basaloid cells which contained keratinous cystic structures with a column of shadow cells arising from basophilic basaloid cells, sebaceous duct-like structures, and ossification in the stroma were also evident. These findings suggest that cutaneous mixed tumors with ossification and hair matrix differentiation are related to both the whole hair follicle and the sweat apparatus.
一名58岁的日本男性患者，其左侧下巴出现了一个含有骨化和毛母质分化的皮肤混合瘤。组织学上，肿瘤几乎完全由顶泌汗腺型上皮导管结构和软骨样间质组成。基底样细胞的条索和聚集也很明显，这些细胞含有角质囊肿结构，有一列由嗜碱性基底样细胞产生的影子细胞、皮脂腺导管样结构以及间质中的骨化。这些发现表明，伴有骨化和毛母质分化的皮肤混合瘤与整个毛囊和汗腺装置都有关。
